Activity of a crude extract formulation in experimental hepatic amoebiasis and in immunomodulation studies
Language: 
English
Abstract: 

The activity of a crude extract formulation was evaluated in experimental amoebic liver abscess in golden hamsters and in immunomodulation studies. The formulation comprises the following five plants-Boerhavia diffusa, Tinospora cordifolia, Berberis aristata, Terminalia chebula and Zingiber officinale. The formulation had a maximum cure rate of 73% at a dose of 800 mg/kg/day in hepatic amoebiasis reducing the average degree of infection (ADI) to 1.3 as compared to 4.2 for sham-treated controls. In immunomodulation studies humoral immunity was enhanced as evidenced by the haemagglutination titre. The T-cell counts remained unaffected in the animals treated with the formulation but cell-mediated immune response was stimulated as observed in the leukocyte migration inhibition (LMI) tests.

Author(s): 
Sohni, Y. R.
Bhatt, R. M.
Item Type: 
Journal Article
Publication Title: 
Journal of Ethnopharmacology
Journal Abbreviation: 
J Ethnopharmacol
Publication Date: 
1996-11
Publication Year: 
1996
Pages: 
119-124
Volume: 
54
Issue: 
3-Feb
ISSN: 
0378-8741
Library Catalog: 
PubMed
Extra: 
PMID: 8953425

Turabian/Chicago Citation

Y. R. Sohni and R. M. Bhatt. 1996-11. "Activity of a crude extract formulation in experimental hepatic amoebiasis and in immunomodulation studies." Journal of Ethnopharmacology 54: 3-Feb: 119-124.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0378-8741 | volume = 54 | pages = 119-124 | last = Sohni | first = Y. R. | coauthors = Bhatt, R. M. | title = Activity of a crude extract formulation in experimental hepatic amoebiasis and in immunomodulation studies | journal = Journal of Ethnopharmacology | date = 1996-11 | pmid = | pmc = }} </ref>