Acupoint application in patients with chronic stable angina pectoris: study protocol of a randomized, double-blind, controlled trial
Language: 
English
Short Title: 
Acupoint application in patients with chronic stable angina pectoris
Abstract: 

Background. Chronic stable angina pectoris (CSAP) is a major syndrome of ischemic heart disease (IHD). CSAP manifests as chest pain or discomfort and affects patients' quality of life. Acupoint application (AP) has been reported to be effective for managing the symptoms of CSAP, but the evidence is not convincing. Therefore, we designed a randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy of AP in the treatment of CSAP. Methods and Analysis. Two hundred participants with CSAP will be randomly assigned in a 1 : 1 : 1 : 1 ratio into 4 groups. All participants will receive 12 sessions of treatment in 4 weeks and the same basic treatment procedure. The participants will be visited and assessed for 12 weeks, including a 4-week screening, a 4-week treatment phase, and a 4-week follow-up phase. The primary outcome is the change in the total frequency of self-reported angina attack at 4th week compared with the baseline. The secondary outcomes include the intensity of angina pain, consumption of nitroglycerin or Suxiao Jiuxin pills, CCS angina classification, SAQ, SAS and SDS score. Ethics. The study protocol has been reviewed and approved by the Sichuan Regional Ethics Review Committee on TCM (number 2013kl-001). This trial is registered with clinicaltrials.gov NCT02029118.

Author(s): 
Ren, Yulan
Li, Dehua
Zheng, Hui
Lv, Junling
Leng, Junyan
Zhang, Linglin
Zhang, Jie
Fan, Hailong
Liang, Fanrong
Item Type: 
Journal Article
Publication Title: 
Evidence-Based Complementary and Alternative Medicine: eCAM
Journal Abbreviation: 
Evid Based Complement Alternat Med
Publication Date: 
2014
Publication Year: 
2014
Pages: 
619706
Volume: 
2014
ISSN: 
1741-427X
DOI: 
10.1155/2014/619706
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 25250055 PMCID: PMC4163288

Turabian/Chicago Citation

Yulan Ren, Dehua Li, Hui Zheng, Junling Lv, Junyan Leng, Linglin Zhang, Jie Zhang, Hailong Fan and Fanrong Liang. 2014. "Acupoint application in patients with chronic stable angina pectoris: study protocol of a randomized, double-blind, controlled trial." Evidence-Based Complementary and Alternative Medicine: eCAM 2014: 619706. 10.1155/2014/619706.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1155/2014/619706 | issn = 1741-427X | volume = 2014 | pages = 619706 | last = Ren | first = Yulan | coauthors = Li, Dehua, Zheng, Hui, Lv, Junling, Leng, Junyan, Zhang, Linglin, Zhang, Jie, Fan, Hailong, Liang, Fanrong | title = Acupoint application in patients with chronic stable angina pectoris: study protocol of a randomized, double-blind, controlled trial | journal = Evidence-Based Complementary and Alternative Medicine: eCAM | date = 2014 | pmid = | pmc = }} </ref>