Acupuncture to Reduce Sleep Disturbances in Perimenopausal and Postmenopausal Women: A Systematic Review and Meta-analysis
Language: 
English
Short Title: 
Acupuncture to Reduce Sleep Disturbances in Perimenopausal and Postmenopausal Women
Abstract: 

OBJECTIVE: To examine the association of acupuncture with sleep disturbances and serum sex hormone levels in perimenopausal and postmenopausal women and whether there are associated changes in sex hormone levels. DATA SOURCES: We systematically searched electronic databases (EMBASE, PubMed, PsycINFO, CINAHL, ClinicalTrials.gov, Wanfang Data Chinese Database, and China Knowledge Resource Integrated Database) and the reference lists of the identified studies. METHODS OF STUDY SELECTION: Randomized controlled trials that examined the effects of acupuncture on sleep disturbances in perimenopausal and postmenopausal women were included. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement was followed. TABULATION, INTEGRATION, AND RESULTS: We identified 31 randomized controlled trials with 34 effect sizes involving a total of 2,433 participants. Acupuncture is associated with a significant reduction in the likelihood of sleep disturbances (odds ratio [OR] 0.21, 95% confidence interval [CI] 0.14-0.31), a significant increase in the secretion of serum estradiol (pooled difference in means 7.56 pg/mL, 95% CI 4.03-11.08), and reduction in the secretion of serum follicle-stimulating hormone (-6.75 milli-international units/mL, 95% CI -12.16 to -1.34) and luteinizing hormone (-2.71 milli-international units/mL, 95% CI -4.22 to -1.20). Studies with a large effect size of acupuncture-associated changes in serum estradiol had a significantly lower odds of sleep disturbances than did those with a small-to-moderate effect sizes (ORs 0.07 and 0.36, P=.02). CONCLUSION: Acupuncture is associated with a significant reduction in sleep disturbances in women experiencing menopause-related sleep disturbances. Our findings suggest that acupuncture should be adopted as part of a multimodal approach for improving sleep disturbances in perimenopausal and postmenopausal women.

Author(s): 
Chiu, Hsiao-Yean
Hsieh, Yu-Jung
Tsai, Pei-Shan
Item Type: 
Journal Article
Publication Title: 
Obstetrics and Gynecology
Journal Abbreviation: 
Obstet Gynecol
Publication Date: 
2016-03
Publication Year: 
2016
Pages: 
507-515
Volume: 
127
Issue: 
3
ISSN: 
1873-233X
DOI: 
10.1097/AOG.0000000000001268
Library Catalog: 
PubMed
Extra: 
PMID: 26855097

Turabian/Chicago Citation

Hsiao-Yean Chiu, Yu-Jung Hsieh and Pei-Shan Tsai. 2016-03. "Acupuncture to Reduce Sleep Disturbances in Perimenopausal and Postmenopausal Women: A Systematic Review and Meta-analysis." Obstetrics and Gynecology 127: 3: 507-515. 10.1097/AOG.0000000000001268.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1097/AOG.0000000000001268 | issn = 1873-233X | volume = 127 | pages = 507-515 | last = Chiu | first = Hsiao-Yean | coauthors = Hsieh, Yu-Jung, Tsai, Pei-Shan | title = Acupuncture to Reduce Sleep Disturbances in Perimenopausal and Postmenopausal Women: A Systematic Review and Meta-analysis | journal = Obstetrics and Gynecology | date = 2016-03 | pmid = | pmc = }} </ref>