An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts
Language: 
English
Abstract: 

Comparative studies of aging are often difficult to interpret because of the different factors that tend to correlate with longevity. We used the AnAge database to study these factors, particularly metabolism and developmental schedules, previously associated with longevity in vertebrate species. Our results show that, after correcting for body mass and phylogeny, basal metabolic rate does not correlate with longevity in eutherians or birds, although it negatively correlates with marsupial longevity and time to maturity. We confirm the idea that age at maturity is typically proportional to adult life span, and show that mammals that live longer for their body size, such as bats and primates, also tend to have a longer developmental time for their body size. Lastly, postnatal growth rates were negatively correlated with adult life span in mammals but not in birds. Our work provides a detailed view of factors related to species longevity with implications for how comparative studies of aging are interpreted.

Author(s): 
de Magalh„es, Jo„o Pedro
Costa, Joana
Church, George M.
Item Type: 
Journal Article
Publication Title: 
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Journal Abbreviation: 
J. Gerontol. A Biol. Sci. Med. Sci.
Publication Date: 
2007-02
Publication Year: 
2007
Pages: 
149-160
Volume: 
62
Issue: 
2
ISSN: 
1079-5006
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 17339640 PMCID: PMC2288695

Turabian/Chicago Citation

Jo„o Pedro de Magalh„es, Joana Costa and George M. Church. 2007-02. "An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 62: 2: 149-160.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 1079-5006 | volume = 62 | pages = 149-160 | last = de Magalh„es | first = Jo„o Pedro | coauthors = Costa, Joana, Church, George M. | title = An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts | journal = The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences | date = 2007-02 | pmid = | pmc = }} </ref>