Animal models for studying homeopathy and high dilutions: conceptual critical review
Language: 
English
Short Title: 
Animal models for studying homeopathy and high dilutions
Abstract: 

INTRODUCTION: This is a systematic review of the animal models used in studies of high dilutions. The objectives are to analyze methodological quality of papers and reported results, and to highlight key conceptual aspects of high dilution to suggest clues concerning putative mechanisms of action. METHODS: Papers for inclusion were identified systematically, from the Pubmed-Medline database, using 'Homeopathy' and 'Animal' as keywords. Only original full papers in English published between January 1999 and June 2009 were included, reviews, scientific reports, thesis, older papers, papers extracted from Medline using similar keywords, papers about mixed commercial formulas and books were also considered for discussion only. 31 papers describing 33 experiments were identified for the main analysis and a total of 89 items cited. RESULTS: Systematic analysis of the selected papers yielded evidence of some important intrinsic features of high dilution studies performed in animal models: a) methodological quality was generally adequate, some aspects could be improved; b) convergence between results and materia medica is seen in some studies, pointing toward to the possibility of systematic study of the Similia principle c) both isopathic and Similia models seem useful to understand some complex biological phenomena, such as parasite-host interactions; d) the effects of high dilutions seem to stimulate restoration of a 'stable state', as seen in several experimental models from both descriptive and mathematical points of view.

Author(s): 
Bonamin, Leoni Villano
Endler, Peter Christian
Item Type: 
Journal Article
Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy
Journal Abbreviation: 
Homeopathy
Publication Date: 
2010-01
Publication Year: 
2010
Pages: 
37-50
Volume: 
99
Issue: 
1
ISSN: 
1476-4245
DOI: 
10.1016/j.homp.2009.11.003
Library Catalog: 
PubMed
Extra: 
PMID: 20129175

Turabian/Chicago Citation

Leoni Villano Bonamin and Peter Christian Endler. 2010-01. "Animal models for studying homeopathy and high dilutions: conceptual critical review." Homeopathy: The Journal of the Faculty of Homeopathy 99: 1: 37-50. 10.1016/j.homp.2009.11.003.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.homp.2009.11.003 | issn = 1476-4245 | volume = 99 | pages = 37-50 | last = Bonamin | first = Leoni Villano | coauthors = Endler, Peter Christian | title = Animal models for studying homeopathy and high dilutions: conceptual critical review | journal = Homeopathy: The Journal of the Faculty of Homeopathy | date = 2010-01 | pmid = | pmc = }} </ref>