Anti-arthritic activity of Indian monocellate cobra (Naja kaouthia) venom on adjuvant induced arthritis
Language: 
English
Abstract: 

The Indian Monocellate Cobra venom (NKV) showed anti-arthritic activity over FCA induced arthritis in male albino rats. NKV treatment (1/20th & 1/10th MLD doses x 13 days, i.p.) showed significant restoration in paw & ankle volume, paw weight. Urinary hydroxyproline, glucosamine, serum ACP, ALP and IL-10 level were restored significantly, due to NKV treatment, as compared with arthritic rats. NKV also showed significant protection against arthritis induced oxidative damages. Thus this study confirmed the scientific validation behind ancient belief and use of snake venom in arthritis as mentioned in Ayurveda.

Author(s): 
Gomes, Antony
Bhattacharya, Sourav
Chakraborty, Mousumi
Bhattacharjee, Pushpak
Mishra, Roshnara
Gomes, Aparna
Item Type: 
Journal Article
Publication Title: 
Toxicon: Official Journal of the International Society on Toxinology
Journal Abbreviation: 
Toxicon
Publication Date: 
2010 Feb-Mar
Publication Year: 
2010
Pages: 
670-673
Volume: 
55
Issue: 
2-3
ISSN: 
1879-3150
DOI: 
10.1016/j.toxicon.2009.10.007
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 19825384

Turabian/Chicago Citation

Antony Gomes, Sourav Bhattacharya, Mousumi Chakraborty, Pushpak Bhattacharjee, Roshnara Mishra and Aparna Gomes. 2010 Feb-Mar. "Anti-arthritic activity of Indian monocellate cobra (Naja kaouthia) venom on adjuvant induced arthritis." Toxicon: Official Journal of the International Society on Toxinology 55: 2-3: 670-673. 10.1016/j.toxicon.2009.10.007.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.toxicon.2009.10.007 | issn = 1879-3150 | volume = 55 | pages = 670-673 | last = Gomes | first = Antony | coauthors = Bhattacharya, Sourav, Chakraborty, Mousumi, Bhattacharjee, Pushpak, Mishra, Roshnara, Gomes, Aparna | title = Anti-arthritic activity of Indian monocellate cobra (Naja kaouthia) venom on adjuvant induced arthritis | journal = Toxicon: Official Journal of the International Society on Toxinology | date = 2010 Feb-Mar | pmid = | pmc = }} </ref>