Aromatherapy as treatment for postoperative nausea: a randomized trial
Short Title: 
Aromatherapy as treatment for postoperative nausea

BACKGROUND: Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in comparison with inhaling a placebo, PON will be reduced significantly by aromatherapy with (1) essential oil of ginger, (2) a blend of essential oils of ginger, spearmint, peppermint, and cardamom, or (3) isopropyl alcohol. Our secondary hypothesis was that the effectiveness of aromatherapy will depend upon the agent used. METHODS: A randomized trial of aromatherapy with patients who reported nausea in the postanesthesia care unit was conducted at one ambulatory surgical center. Eligibility criteria were adult, able to give consent, and no history of coagulation problems or allergy to the aromatherapy agents. Before surgery, demographic and risk factors were collected. Patients with a nausea level of 1 to 3 on a verbal descriptive scale (0-3) received a gauze pad saturated with a randomly chosen aromatherapy agent and were told to inhale deeply 3 times; nausea (0-3) was then measured again in 5 minutes. Prophylactic and postnausea antiemetics were given as ordered by physicians or as requested by the patient. RESULTS: A total of 1151 subjects were screened for inclusion; 303 subjects reporting nausea were enrolled (26.3%), and 301 meeting protocol were analyzed (26.2%). The change in nausea level was significant for the blend (P < 0.001) and ginger (P = 0.002) versus saline but not for alcohol (P < 0.76). The number of antiemetic medications requested after aromatherapy was also significantly reduced with ginger or blend aromatherapy versus saline (P = 0.002 and P < 0.001, respectively). CONCLUSION: The hypothesis that aromatherapy would be effective as a treatment for PON was supported. On the basis of our results, future research further evaluating aromatherapy is warranted. Aromatherapy is promising as an inexpensive, noninvasive treatment for PON that can be administered and controlled by patients as needed.

Hunt, Ronald
Dienemann, Jacqueline
Norton, H. James
Hartley, Wendy
Hudgens, Amanda
Stern, Thomas
Divine, George
Item Type: 
Journal Article
Publication Title: 
Anesthesia and Analgesia
Journal Abbreviation: 
Anesth. Analg.
Publication Date: 
Publication Year: 
Library Catalog: 
PMID: 22392970

Turabian/Chicago Citation

Ronald Hunt, Jacqueline Dienemann, H. James Norton, Wendy Hartley, Amanda Hudgens, Thomas Stern and George Divine. 9/13/2015. "Aromatherapy as treatment for postoperative nausea: a randomized trial." Anesthesia and Analgesia 117: 3: 597-604. 10.1213/ANE.0b013e31824a0b1c.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1213/ANE.0b013e31824a0b1c | issn = 1526-7598 | volume = 117 | pages = 597-604 | last = Hunt | first = Ronald | coauthors = Dienemann, Jacqueline, Norton, H. James, Hartley, Wendy, Hudgens, Amanda, Stern, Thomas, Divine, George | title = Aromatherapy as treatment for postoperative nausea: a randomized trial | journal = Anesthesia and Analgesia | date = 9/13/2015 | pmid = | pmc = }} </ref>