Ayurvedic medicine and renal calculi
Language: 
English
Abstract: 

OBJECTIVE: To explore the supportive evidence for the use of Ayurvedic medicine in the management of existing and recurrent nephrolithiasis. METHOD: Nine Ayurvedic medicines commonly utilized in the management of nephrolithiasis were identified by discussions with Ayurvedic practitioners in India. Mechanistic and clinical studies evaluating the use of these agents were identified using the Medline database and bibliographies suggested by Ayurvedic practitioners. The articles were then critically reviewed and summarized. RESULTS: Four in vitro mechanistic studies, eight animal studies, and seven human trials were identified. Phyllanthus niruri has undergone mechanistic in vitro, animal, and clinical trials that support its impact on calcium oxalate crystallization. Preliminary clinical trials have evaluated the role of Dolichos biflorus and Orthosiphon grandiflorus in the prevention of urolithiasis and fish stone as a method of stone expulsion, yet the treatment effect and mechanism of action remains to be elucidated. CONCLUSION: Ayurvedic medicine holds promise as a complementary approach to the management and prevention of nephrolithiasis. The best studied compound is P. niruri. Further controlled randomized clinical trials are justified to support or refute the potential benefits demonstrated in these initial studies.

Author(s): 
Kieley, Sam
Dwivedi, Roli
Monga, Manoj
Item Type: 
Journal Article
Publication Title: 
Journal of Endourology / Endourological Society
Journal Abbreviation: 
J. Endourol.
Publication Date: 
Aug 2008
Publication Year: 
2008
Pages: 
1613-1616
Volume: 
22
Issue: 
8
ISSN: 
1557-900X
DOI: 
10.1089/end.2008.0020
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 18620498

Turabian/Chicago Citation

Sam Kieley, Roli Dwivedi and Manoj Monga. Aug 2008. "Ayurvedic medicine and renal calculi." Journal of Endourology / Endourological Society 22: 8: 1613-1616. 10.1089/end.2008.0020.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1089/end.2008.0020 | issn = 1557-900X | volume = 22 | pages = 1613-1616 | last = Kieley | first = Sam | coauthors = Dwivedi, Roli, Monga, Manoj | title = Ayurvedic medicine and renal calculi | journal = Journal of Endourology / Endourological Society | date = Aug 2008 | pmid = | pmc = }} </ref>