Calorie restriction in primates: will it work and how will we know?
Language: 
English
Short Title: 
Calorie restriction in primates
Abstract: 

Dietary caloric restriction is the most robust and reproducible means of slowing aging and extending lifespan and healthspan in short-lived mammals and lower organisms. Numerous aspects of this paradigm have been investigated in laboratories around the world since its inception more than 60 years ago. However, two questions about calorie restriction remain unanswered to this day: (1) By what mechanism does it work? and (2) Will it work in humans? This review will focus on the latter with particular emphasis on evaluation criteria, current studies in primate models, available data, and plans for actual human caloric restriction interventions.

Author(s): 
Roth, G. S.
Ingram, D. K.
Lane, M. A.
Item Type: 
Journal Article
Publication Title: 
Journal of the American Geriatrics Society
Journal Abbreviation: 
J Am Geriatr Soc
Publication Date: 
1999-07
Publication Year: 
1999
Pages: 
896-903
Volume: 
47
Issue: 
7
ISSN: 
0002-8614
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 10404938

Turabian/Chicago Citation

G. S. Roth, D. K. Ingram and M. A. Lane. 1999-07. "Calorie restriction in primates: will it work and how will we know?." Journal of the American Geriatrics Society 47: 7: 896-903.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0002-8614 | volume = 47 | pages = 896-903 | last = Roth | first = G. S. | coauthors = Ingram, D. K., Lane, M. A. | title = Calorie restriction in primates: will it work and how will we know? | journal = Journal of the American Geriatrics Society | date = 1999-07 | pmid = | pmc = }} </ref>