Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD
Language: 
English
Abstract: 

Abhayarishta is an Ayurvedic formulation prepared traditionally by the fermentation of the decoction of Terminalia chebula (pericarp), Vitis vinifera (fruits), Embelia ribes (fruits) and Madhuca indica (flowers). In the present communication, chemical changes occurring during fermentation in Abhayarishta have been studied for the purpose of its standardization. An HPLC-DAD method for quantitative estimation of selected marker constituents in the formulation has been developed and validated. A comparison of decoction and final processed formulation revealed that major polyphenolics (chebulagic and chebulinic acid) of T. chebula were hydrolyzed to their respective monomers and, consequently, there was an increase in the amount of chebulic acid, gallic acid, ellagic acid and ethyl gallate after fermentation. 5-Hydroxymethyl furfural (5-HMF) was also found in the formulation. Thus, emphasis is laid upon consideration of processing methods of formulation which has been lacking in the standardization of most of Ayurvedic formulations.

Author(s): 
Lal, Uma Ranjan
Tripathi, Shailendra Mani
Jachak, Sanjay M.
Bhutani, Kamlesh Kumar
Singh, Inder Pal
Item Type: 
Journal Article
Publication Title: 
Natural Product Communications
Journal Abbreviation: 
Nat Prod Commun
Publication Date: 
2010-04
Publication Year: 
2010
Pages: 
575-579
Volume: 
5
Issue: 
4
ISSN: 
1934-578X
Library Catalog: 
PubMed
Extra: 
PMID: 20433076

Turabian/Chicago Citation

Uma Ranjan Lal, Shailendra Mani Tripathi, Sanjay M. Jachak, Kamlesh Kumar Bhutani and Inder Pal Singh. 2010-04. "Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD." Natural Product Communications 5: 4: 575-579.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 1934-578X | volume = 5 | pages = 575-579 | last = Lal | first = Uma Ranjan | coauthors = Tripathi, Shailendra Mani, Jachak, Sanjay M., Bhutani, Kamlesh Kumar, Singh, Inder Pal | title = Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD | journal = Natural Product Communications | date = 2010-04 | pmid = | pmc = }} </ref>