Chemical identification of the sources of commercial Fructus Chebulae
Language: 
English
Abstract: 

Twenty-eight commercial samples of Fructus Chebulae were collected from local herbal markets in Taiwan and were determined to have been derived from Terminalia chebula Retz. and Terminalia chebula Retz. var. parviflora Thwaites, which differ markedly in external appearance. Ten tannin-related constituents [gallic acid (1), chebulic acid (2), punicalagin (4), chebulanin (7), corilagin (8), neochebulinic acid (9), ellagic acid (11), chebulagic acid (12), chebulinic acid (13) and 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (14)] were identified and quantified by HPLC. Samples derived from T. chebula. var. parviflora, which are typically round-shaped, generally contained higher concentrations of 13 and 14 but lower levels of 12 compared with those from T. chebula, which are largely oval-shaped. The ratio of the concentration of 14 to that of 4 may serve as a potential parameter for differentiating samples from the two origins (T. chebula, ratio 0.6 +/- 0.3; T. chebula. var. parviflora, ratio 3.4 +/- 2.2). Levels of the three major bioactive constituents 12-14 were found to provide good references for the quality assessment of Fructus Chebulae. The ratio of the concentration of 12 to that of 14 may offer a guideline for determining quality as well as origin of the drug (lower-grade T. chebula, ratio 12.4 +/- 6.0; medium-grade T. chebula, ratio 8.8 +/- 7.9; higher-grade T. chebula, ratio 3.2 +/- 0.8; T. chebula var. parviflora, ratio 1.6 +/- 0.7).

Author(s): 
Juang, Lih-Jeng
Sheu, Shuenn-Jyi
Item Type: 
Journal Article
Publication Title: 
Phytochemical analysis: PCA
Journal Abbreviation: 
Phytochem Anal
Publication Date: 
2005-08
Publication Year: 
2005
Pages: 
246-251
Volume: 
16
Issue: 
4
ISSN: 
0958-0344
Library Catalog: 
PubMed
Extra: 
PMID: 16042149

Turabian/Chicago Citation

Lih-Jeng Juang and Shuenn-Jyi Sheu. 2005-08. "Chemical identification of the sources of commercial Fructus Chebulae." Phytochemical analysis: PCA 16: 4: 246-251.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0958-0344 | volume = 16 | pages = 246-251 | last = Juang | first = Lih-Jeng | coauthors = Sheu, Shuenn-Jyi | title = Chemical identification of the sources of commercial Fructus Chebulae | journal = Phytochemical analysis: PCA | date = 2005-08 | pmid = | pmc = }} </ref>