Is DDD superior to VVI pacing in mixed carotid sinus syndrome? An acute and medium-term study
Language: 
English
Short Title: 
Is DDD superior to VVI pacing in mixed carotid sinus syndrome?
Abstract: 

The aim of this study was to evaluate the importance of atrial synchronism for pacing therapy of patients with mixed carotid sinus syndrome. In 23 patients (21 m, two f; mean age 69 +/- 8 years) affected by symptomatic mixed carotid sinus syndrome we performed: (1) Research of ventriculo-atrial conduction, orthostatic hypotension and pacemaker effect; and (2) Carotid sinus massage in the standing position during VVI and DVI temporary pacing. Next, all patients received a permanent DDD pacemaker and entered a 2 month two period single-blind, randomized, cross-over study on DVI/DDD versus VVI mode. During the DVI/DDD period, no syncope occurred in any patients, minor symptoms persisted in 11 (48%) of them; during VVI period syncopes recurred in three patients, symptoms requiring the withdrawal of VVI pacing and premature DVI/DDD reprogramming in eight patients, minor symptoms in 17 (74%). A comparison between 14 patients, who preferred DVI/DDD period (Group A), and the remaining nine patients who noted no preference between DVI/DDD and VVI period (Group B) was performed on the basis of the preimplant evaluation. Group A patients had a greater pacemaker effect (-34 +/- 16 mmHg vs -16 +/- 14 mmHg) and a higher prevalence of symptomatic pacemaker effect (50% vs 0%), of ventriculo-atrial conduction (78% vs 44%) and of orthostatic hypotension (50% vs 11%), while the entity of the systolic pressure fall caused by carotid sinus massage was similar in the two groups either during VVI mode (Group A -51 +/- 16 mmHg vs Group B -56 +/- 27 mmHg) or DVI mode (Group A -38 +/- 17 mmHg vs Group B -45 +/- 17 mmHg).(ABSTRACT TRUNCATED AT 250 WORDS)

Author(s): 
Brignole, M.
Sartore, B.
Barra, M.
Menozzi, C.
Lolli, G.
Item Type: 
Journal Article
Publication Title: 
Pacing and clinical electrophysiology: PACE
Journal Abbreviation: 
Pacing Clin Electrophysiol
Publication Date: 
Nov 1988
Publication Year: 
1988
Pages: 
1902-1910
Volume: 
11
Issue: 
11 Pt 2
ISSN: 
0147-8389
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 2463565

Turabian/Chicago Citation

M. Brignole, B. Sartore, M. Barra, C. Menozzi and G. Lolli. Nov 1988. "Is DDD superior to VVI pacing in mixed carotid sinus syndrome? An acute and medium-term study." Pacing and clinical electrophysiology: PACE 11: 11 Pt 2: 1902-1910.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0147-8389 | volume = 11 | pages = 1902-1910 | last = Brignole | first = M. | coauthors = Sartore, B., Barra, M., Menozzi, C., Lolli, G. | title = Is DDD superior to VVI pacing in mixed carotid sinus syndrome? An acute and medium-term study | journal = Pacing and clinical electrophysiology: PACE | date = Nov 1988 | pmid = | pmc = }} </ref>