Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride: an 8-week clinical study on Chinese adults
Language: 
English
Short Title: 
Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride
Abstract: 

PURPOSE: To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP. METHODS: An 8-week clinical study, with 121 subjects, was conducted in Chengdu, Sichuan, China, using a double-blind, stratified, three-treatment design. Tactile and air blast sensitivity assessments were used to compare the efficacy of the three products. RESULTS: This clinical study demonstrated that the new Pro-Argin formula toothpaste provided a significant reduction in dentin hypersensitivity when used over a period of 8 weeks. The study also showed that the new toothpaste provided significantly greater reductions (P < 0.05) in dentin hypersensitivity in response to tactile (64.4%, 71.1%, and 61.0%) and air blast (40.7%, 58.8%, and 74.4%) stimuli than the negative control toothpaste containing 1450 ppm fluoride after 2, 4, and 8 weeks of product use, respectively. The results for the new toothpaste did not differ significantly from those of the positive control toothpaste at all time points in the study.

Author(s): 
Que, Kehua
Fu, Yingying
Lin, Lin
Hu, Deyu
Zhang, Yun Po
Panagakos, Fotinos S.
DeVizio, William
Mateo, Luis R.
Item Type: 
Journal Article
Publication Title: 
American Journal of Dentistry
Journal Abbreviation: 
Am J Dent
Publication Date: 
May 2010
Publication Year: 
2010
Pages: 
28A-35A
Volume: 
23 Spec No A
ISSN: 
0894-8275
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 21284249

Turabian/Chicago Citation

Kehua Que, Yingying Fu, Lin Lin, Deyu Hu, Yun Po Zhang, Fotinos S. Panagakos, William DeVizio and Luis R. Mateo. May 2010. "Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride: an 8-week clinical study on Chinese adults." American Journal of Dentistry 23 Spec No A: 28A-35A.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0894-8275 | volume = 23 Spec No A | pages = 28A-35A | last = Que | first = Kehua | coauthors = Fu, Yingying, Lin, Lin, Hu, Deyu, Zhang, Yun Po, Panagakos, Fotinos S., DeVizio, William, Mateo, Luis R. | title = Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride: an 8-week clinical study on Chinese adults | journal = American Journal of Dentistry | date = May 2010 | pmid = | pmc = }} </ref>