Dimorphic changes of some features of loving relationships during long-term use of antidepressants in depressed outpatients
Language: 
English
Abstract: 

The present study aimed at investigating the possible changes of some features of loving relationships during long-term treatment of depression with both selective serotonin reuptake inhibitors (SSRIs) and tricyclics (TCAs), by means of a specifically designed test, the so-called "Sex, Attachment, Love" (SALT) questionnaire. The sample was composed by 192 outpatients (123 women and 69 men, mean age±SD: 41.2±10.2 years), suffering from mild or moderate depression, according to DSM-IV-TR criteria, that were selected if they were treated with one antidepressant only for at least six months and were involved in a loving relationship. The results showed that SSRIs had a significant impact on the feelings of love and attachment towards the partner especially in men, while women taking TCAs complained of more sexual side effects than men. These data were supported also by the detection of a significant interaction between drug and sex on the "Love" and "Sex" domains. The present findings, while demonstrating a dimorphic effect of antidepressants on some component of loving relationships, need to be deepened in future studies.

Author(s): 
Marazziti, Donatella
Akiskal, Hagop S.
Udo, Mieko
Picchetti, Michela
Baroni, Stefano
Massimetti, Gabriele
Albanese, Francesco
Dell'Osso, Liliana
Item Type: 
Journal Article
Publication Title: 
Journal of Affective Disorders
Journal Abbreviation: 
J Affect Disord
Publication Date: 
2014-09
Publication Year: 
2014
Pages: 
151-155
Volume: 
166
ISSN: 
1573-2517
DOI: 
10.1016/j.jad.2014.04.043
Library Catalog: 
PubMed
Extra: 
PMID: 25012424

Turabian/Chicago Citation

Donatella Marazziti, Hagop S. Akiskal, Mieko Udo, Michela Picchetti, Stefano Baroni, Gabriele Massimetti, Francesco Albanese and Liliana Dell'Osso. 2014-09. "Dimorphic changes of some features of loving relationships during long-term use of antidepressants in depressed outpatients." Journal of Affective Disorders 166: 151-155. 10.1016/j.jad.2014.04.043.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.jad.2014.04.043 | issn = 1573-2517 | volume = 166 | pages = 151-155 | last = Marazziti | first = Donatella | coauthors = Akiskal, Hagop S., Udo, Mieko, Picchetti, Michela, Baroni, Stefano, Massimetti, Gabriele, Albanese, Francesco, Dell'Osso, Liliana | title = Dimorphic changes of some features of loving relationships during long-term use of antidepressants in depressed outpatients | journal = Journal of Affective Disorders | date = 2014-09 | pmid = | pmc = }} </ref>