Effects of mind-body exercises on the physiological and psychosocial well-being of individuals with Parkinson's disease: A systematic review and meta-analysis
Language: 
English
Short Title: 
Effects of mind-body exercises on the physiological and psychosocial well-being of individuals with Parkinson's disease
Abstract: 

OBJECTIVES: The effects of mind-body exercises on individuals with chronic illnesses have attracted increasing attention. However, little effort had been made to systematically review the effects of these mind-body exercises on individuals with Parkinson's disease (PD). This review aimed to appraise the current evidence of the effects of mind-body exercises on the physiological and psychological outcomes for the PD population. DESIGN: Systematic review and meta-analysis of randomized controlled trials. DATA SOURCES: Four English databases, namely, the EMBASE, Ovid Medline, Psych Info, and Cochrane Library, were searched on January 2016. REVIEW METHODS: Studies involving participants with idiopathic PD were included if mind-body exercises were applied and compared with a non-exercise control to improve physiological and psychosocial well-being. The Effective Public Health Practice Project quality assessment tool was used for quality appraisal. RevMan 5.3 was employed to perform this meta-analysis. A subgroup analysis regarding the types and the dose of intervention was conducted to explore the sources of heterogeneity. RESULTS: Ten studies met the inclusion criteria for quality appraisal. The overall methodological rating of these studies indicated that one study was strong; five studies were moderate; and four studies were weak. Nine articles comprising five Tai Chi, two yoga, and two dance studies were included in the meta-analysis. The results of this review showed that mind-body exercises had a large, significant beneficial effect in motor symptoms in terms of UPDRS III for people with mild to moderate PD [SMD=-0.91, 95% CI (-1.37, -0.45), p<0.05]. Significant subgroup differences were found among various types of mind-body exercises (p=0.001). Yoga demonstrated the largest and most significant beneficial effect in reducing UPDRS III scores [SMD=-2.35, 95% CI (-3.21, -1.50), p<0.01]. The pooled meta-analysis results showed that mind-body exercises had a large, significant effect in improving postural instability in terms of the Berg Balance Scale [SMD=1.48, 95% CI (0.91, 2.06), p<0.01] and Timed Up and Go test [SMD=-0.97, 95% CI (-1.46, -0.47), p<0.01] and moderate, significant effect in improving functional mobility in terms of the Six-minute Walk test [SMD=0.78, 95% CI (0.35, 1.21), p<0.05]. CONCLUSIONS: This review found that mind-body exercises demonstrated immediate moderate to large beneficial effects on motor symptoms, postural instability, and functional mobility among individuals with mild to moderate PD. However, the effects of mind-body exercises on psychosocial well-being had not been amply investigated, especially for yoga intervention. Future research should address the psychosocial effects of mind-body exercises on the PD population.

Author(s): 
Kwok, JoJo Yan Yan
Choi, Kai Chow
Chan, Helen Yue Lai
Item Type: 
Journal Article
Publication Title: 
Complementary Therapies in Medicine
Journal Abbreviation: 
Complement Ther Med
Publication Date: 
2016-12
Publication Year: 
2016
Pages: 
121-131
Volume: 
29
ISSN: 
1873-6963
DOI: 
10.1016/j.ctim.2016.09.016
Library Catalog: 
PubMed
Extra: 
PMID: 27912936

Turabian/Chicago Citation

JoJo Yan Yan Kwok, Kai Chow Choi and Helen Yue Lai Chan. 2016-12. "Effects of mind-body exercises on the physiological and psychosocial well-being of individuals with Parkinson's disease: A systematic review and meta-analysis." Complementary Therapies in Medicine 29: 121-131. 10.1016/j.ctim.2016.09.016.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.ctim.2016.09.016 | issn = 1873-6963 | volume = 29 | pages = 121-131 | last = Kwok | first = JoJo Yan Yan | coauthors = Choi, Kai Chow, Chan, Helen Yue Lai | title = Effects of mind-body exercises on the physiological and psychosocial well-being of individuals with Parkinson's disease: A systematic review and meta-analysis | journal = Complementary Therapies in Medicine | date = 2016-12 | pmid = | pmc = }} </ref>