Firstborn microcrystallization method to prepare nanocapsules containing artesunate
Language: 
English
Abstract: 

We developed a novel method to prepare nanocapsules. A solute often crystallizes when its solubility alters from one solvent to another, and its firstborn crystals are used as templates to prepare nanocapsules for the first time, which is called firstborn microcrystallization method. By using this method, the maximum diameter of the nanocapsules including artesunate is about 76 nm, and wrapping state is well. One important advantage of our method is that the preparation of the nanocapsules operates easily and is a one-time process with no other cumbersome processes necessary, therefore avoiding secondary pollution. The proposed method provides a new route to prepare monodisperse nanocapsules to increase bioavailability of hydrophobic solutes.

Author(s): 
Xiao, Xin-Cai
Hong, Zong-Guo
Item Type: 
Journal Article
Publication Title: 
International Journal of Nanomedicine
Journal Abbreviation: 
Int J Nanomedicine
Publication Date: 
2010
Publication Year: 
2010
Pages: 
483-486
Volume: 
5
ISSN: 
1178-2013
Library Catalog: 
PubMed
Extra: 
PMID: 20957170 PMCID: PMC2950406

Turabian/Chicago Citation

Xin-Cai Xiao and Zong-Guo Hong. 2010. "Firstborn microcrystallization method to prepare nanocapsules containing artesunate." International Journal of Nanomedicine 5: 483-486.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 1178-2013 | volume = 5 | pages = 483-486 | last = Xiao | first = Xin-Cai | coauthors = Hong, Zong-Guo | title = Firstborn microcrystallization method to prepare nanocapsules containing artesunate | journal = International Journal of Nanomedicine | date = 2010 | pmid = | pmc = }} </ref>