Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats
Language: 
English
Abstract: 

We undertook the present study to evaluate the hypolipidaemic effect of an aqueous extract of Tinospora cordifolia roots, an indigenous plant used in Ayurvedic medicine in India. Administration of the extract of T. cordifolia roots (2.5 and 5.0 g/kg body weight) for 6 weeks resulted in a significant reduction in serum and tissue cholesterol, phospholipids and free fatty acids in alloxan diabetic rats. The root extract at a dose of 5.0 g/kg body weight showed highest hypolipidaemic effect. The effect of T. cordifolia roots at 2.5 and 5.0 g/kg body weight was better than glibenclamide. Insulin restored all the parameters to near normal values.

Author(s): 
Stanely Mainzen Prince, P.
Menon, V. P.
Gunasekaran, G.
Item Type: 
Journal Article
Publication Title: 
Journal of Ethnopharmacology
Journal Abbreviation: 
J Ethnopharmacol
Publication Date: 
Jan 1999
Publication Year: 
1999
Pages: 
53-57
Volume: 
64
Issue: 
1
ISSN: 
0378-8741
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 10075122

Turabian/Chicago Citation

P. Stanely Mainzen Prince, V. P. Menon and G. Gunasekaran. Jan 1999. "Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats." Journal of Ethnopharmacology 64: 1: 53-57.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0378-8741 | volume = 64 | pages = 53-57 | last = Stanely Mainzen Prince | first = P. | coauthors = Menon, V. P., Gunasekaran, G. | title = Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats | journal = Journal of Ethnopharmacology | date = Jan 1999 | pmid = | pmc = }} </ref>