Implications of a mathematical model for the role of lymphocytes with different lifespans in the recovery from tolerance
Language: 
English
Abstract: 

An extension of the mathematical model of immunological tolerance including two categories of B and T helper cells, each having a different lifespan, is presented. The simulated recovery from tolerance is compared with experimental data on B and T helper cell tolerance to human gamma globulin (HGG) induced in adult mice. The performed simulation runs suggest the conclusion that in this case it seems impossible to incorporate a high ratio of both, long-lived B cells and/or short-lived T helper cells, if good agreement with the available experimental data should be preserved.

Author(s): 
Dolezal, J.
Hraba, T.
Item Type: 
Journal Article
Publication Title: 
Folia Biologica
Journal Abbreviation: 
Folia Biol. (Praha)
Publication Date: 
1987
Publication Year: 
1987
Pages: 
356-362
Volume: 
33
Issue: 
5
ISSN: 
0015-5500
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 2446934

Turabian/Chicago Citation

J. Dolezal and T. Hraba. 1987. "Implications of a mathematical model for the role of lymphocytes with different lifespans in the recovery from tolerance." Folia Biologica 33: 5: 356-362.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0015-5500 | volume = 33 | pages = 356-362 | last = Dolezal | first = J. | coauthors = Hraba, T. | title = Implications of a mathematical model for the role of lymphocytes with different lifespans in the recovery from tolerance | journal = Folia Biologica | date = 1987 | pmid = | pmc = }} </ref>