Kinematic determinants of anterior knee pain in cerebral palsy: a case-control study
Language: 
English
Short Title: 
Kinematic determinants of anterior knee pain in cerebral palsy
Abstract: 

OBJECTIVE: To quantify the role patellofemoral and tibiofemoral kinematics may play in development of anterior knee pain (AKP) in individuals with cerebral palsy (CP). DESIGN: Case-control. SETTING: Clinical research center. PARTICIPANTS: Knees from individuals with diagnosed CP (n=20) and control knees (n=40) were evaluated. Controls were matched for sex and age based on the group average. Matching by height and weight was a secondary priority. Subjects in the control cohort were asymptomatic with no history of lower leg abnormalities, surgery, or major injury. Only individuals who were physically capable of sustaining slow, cyclic knee flexion-extension for 2.5 minutes and had no contraindications to magnetic resonance imaging were enrolled. Both groups were samples of convenience. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Three-dimensional patellofemoral and tibiofemoral joint kinematics, acquired during active leg extension, under volitional control. RESULTS: Participants with CP and AKP (n=8) demonstrated significantly greater patellofemoral extension, valgus rotation, and superior and posterior displacement relative to controls and to the subgroup of participants with CP and no AKP (n=12). Patellofemoral extension discriminated AKP in individuals with CP with 100% accuracy. CONCLUSIONS: In quantifying the 3-dimensional, in vivo knee joint kinematics during a volitional extension task, kinematic markers that discriminate AKP in individuals with CP were identified. This provides an ability to predict which individuals with CP are most likely to develop AKP and could enable aggressive conservative treatment, aimed at reducing patella alta and excessive patellofemoral extension, to be prescribed before considering surgical options. The current findings will likely lead to improved clinical diagnostics and interventions for individuals with CP, with the ultimate goal of helping maintain, if not improve, functional mobility throughout the lifespan.

Author(s): 
Sheehan, Frances T.
Babushkina, Anna
Alter, Katharine E.
Item Type: 
Journal Article
Publication Title: 
Archives of Physical Medicine and Rehabilitation
Journal Abbreviation: 
Arch Phys Med Rehabil
Publication Date: 
2012-08
Publication Year: 
2012
Pages: 
1431-1440
Volume: 
93
Issue: 
8
ISSN: 
1532-821X
DOI: 
10.1016/j.apmr.2012.03.022
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 22465585 PMCID: PMC3568741

Turabian/Chicago Citation

Frances T. Sheehan, Anna Babushkina and Katharine E. Alter. 2012-08. "Kinematic determinants of anterior knee pain in cerebral palsy: a case-control study." Archives of Physical Medicine and Rehabilitation 93: 8: 1431-1440. 10.1016/j.apmr.2012.03.022.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.apmr.2012.03.022 | issn = 1532-821X | volume = 93 | pages = 1431-1440 | last = Sheehan | first = Frances T. | coauthors = Babushkina, Anna, Alter, Katharine E. | title = Kinematic determinants of anterior knee pain in cerebral palsy: a case-control study | journal = Archives of Physical Medicine and Rehabilitation | date = 2012-08 | pmid = | pmc = }} </ref>