Molecular mechanisms of age-related sleep loss in the fruit fly - a mini-review
Language: 
English
Abstract: 

Across phyla, aging is associated with reduced sleep duration and efficiency. Both aging and sleep involve complex genetic architecture and diverse cell types and are heavily influenced by diet and environment. Therefore, understanding the molecular mechanisms of age-dependent changes in sleep will require integrative approaches that go beyond examining these two processes independently. The fruit fly, Drosophila melanogaster, provides a genetically amenable system for dissecting the molecular basis of these processes. In this review, we examine the role of metabolism and circadian rhythms in age-dependent sleep loss.

Author(s): 
Robertson, Meagan
Keene, Alex C.
Item Type: 
Journal Article
Publication Title: 
Gerontology
Journal Abbreviation: 
Gerontology
Publication Date: 
2013
Publication Year: 
2013
Pages: 
334-339
Volume: 
59
Issue: 
4
ISSN: 
1423-0003
DOI: 
10.1159/000348576
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 23594925 PMCID: PMC4006093

Turabian/Chicago Citation

Meagan Robertson and Alex C. Keene. 2013. "Molecular mechanisms of age-related sleep loss in the fruit fly - a mini-review." Gerontology 59: 4: 334-339. 10.1159/000348576.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1159/000348576 | issn = 1423-0003 | volume = 59 | pages = 334-339 | last = Robertson | first = Meagan | coauthors = Keene, Alex C. | title = Molecular mechanisms of age-related sleep loss in the fruit fly - a mini-review | journal = Gerontology | date = 2013 | pmid = | pmc = }} </ref>