Nephrolithiasis after bariatric surgery for obesity
Language: 
English
Abstract: 

Surgical intervention has become an accepted therapeutic alternative for the patient with medically complicated obesity. Multiple investigators have reported significant and sustained weight loss after bariatric surgery that is associated with improvement of many weight-related medical comorbidities, and statistically significant decreased overall mortality for surgically treated as compared with medically treated subjects. Although the Roux-en-Y gastric bypass (RYGB) is considered an acceptably safe treatment, an increasing number of patients are being recognized with nephrolithiasis after this, the most common bariatric surgery currently performed. The main risk factor appears to be hyperoxaluria, although low urine volume and citrate concentrations may contribute. The incidence of these urinary risk factors among the total post-RYGB population is unknown, but may be more than previously suspected based on small pilot studies. The etiology of the hyperoxaluria is unknown, but may be related to subtle and seemingly subclinical fat malabsorption. Clearly, further study is needed, especially to define better treatment options than the standard advice for a low-fat, low-oxalate diet, and use of calcium as an oxalate binder.

Author(s): 
Lieske, John C.
Kumar, Rajiv
Collazo-Clavell, Maria L.
Item Type: 
Journal Article
Publication Title: 
Seminars in Nephrology
Journal Abbreviation: 
Semin. Nephrol.
Publication Date: 
Mar 2008
Publication Year: 
2008
Pages: 
163-173
Volume: 
28
Issue: 
2
ISSN: 
0270-9295
DOI: 
10.1016/j.semnephrol.2008.01.009
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 18359397 PMCID: PMC2831413

Turabian/Chicago Citation

John C. Lieske, Rajiv Kumar and Maria L. Collazo-Clavell. Mar 2008. "Nephrolithiasis after bariatric surgery for obesity." Seminars in Nephrology 28: 2: 163-173. 10.1016/j.semnephrol.2008.01.009.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.semnephrol.2008.01.009 | issn = 0270-9295 | volume = 28 | pages = 163-173 | last = Lieske | first = John C. | coauthors = Kumar, Rajiv, Collazo-Clavell, Maria L. | title = Nephrolithiasis after bariatric surgery for obesity | journal = Seminars in Nephrology | date = Mar 2008 | pmid = | pmc = }} </ref>