New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound
Language: 
English
Abstract: 

The chronological lifespan (CLS) of budding yeast is a model for the aging of post-mitotic cells in higher eukaryotes. We report here the development of a new method to assess yeast CLS. The new assay is simple, convenient and labor-saving. We applied this new method to screen natural compounds isolated from mushrooms and discovered beauveriolide I as a potent anti-aging agent.

Author(s): 
Nakaya, Shigeru
Mizuno, Saki
Ishigami, Hiroki
Yamakawa, Yasuhiro
Kawagishi, Hirokazu
Ushimaru, Takashi
Item Type: 
Journal Article
Publication Title: 
Bioscience, Biotechnology, and Biochemistry
Journal Abbreviation: 
Biosci. Biotechnol. Biochem.
Publication Date: 
2012
Publication Year: 
2012
Pages: 
1226-1228
Volume: 
76
Issue: 
6
ISSN: 
1347-6947
DOI: 
10.1271/bbb.110872
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 22790951

Turabian/Chicago Citation

Shigeru Nakaya, Saki Mizuno, Hiroki Ishigami, Yasuhiro Yamakawa, Hirokazu Kawagishi and Takashi Ushimaru. 2012. "New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound." Bioscience, Biotechnology, and Biochemistry 76: 6: 1226-1228. 10.1271/bbb.110872.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1271/bbb.110872 | issn = 1347-6947 | volume = 76 | pages = 1226-1228 | last = Nakaya | first = Shigeru | coauthors = Mizuno, Saki, Ishigami, Hiroki, Yamakawa, Yasuhiro, Kawagishi, Hirokazu, Ushimaru, Takashi | title = New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound | journal = Bioscience, Biotechnology, and Biochemistry | date = 2012 | pmid = | pmc = }} </ref>