Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review
Language: 
English
Short Title: 
Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV
Abstract: 

Chronic pain occurs in as many as 85% of individuals with HIV and is associated with substantial functional impairment. Little guidance is available for HIV providers seeking to address their patients' chronic pain. We conducted a systematic review to identify clinical trials and observational studies that examined the impact of pharmacologic or non-pharmacologic interventions on pain and/or functional outcomes among HIV-infected individuals with chronic pain in high-development countries. Eleven studies met inclusion criteria and were mostly low or very low quality. Seven examined pharmacologic interventions (gabapentin, pregabalin, capsaicin, analgesics including opioids) and four examined non-pharmacologic interventions (cognitive behavioral therapy, self-hypnosis, smoked cannabis). The only controlled studies with positive results were of capsaicin and cannabis, and had short-term follow-up (?12 weeks). Among the seven studies of pharmacologic interventions, five had substantial pharmaceutical industry sponsorship. These findings highlight several important gaps in the HIV/chronic pain literature that require further research.

Author(s): 
Merlin, Jessica S.
Bulls, Hailey W.
Vucovich, Lee A.
Edelman, E. Jennifer
Starrels, Joanna L.
Item Type: 
Journal Article
Publication Title: 
AIDS care
Journal Abbreviation: 
AIDS Care
Publication Date: 
2016-12
Publication Year: 
2016
Pages: 
1506-1515
Volume: 
28
Issue: 
12
ISSN: 
1360-0451
DOI: 
10.1080/09540121.2016.1191612
Library Catalog: 
PubMed
Extra: 
PMID: 27267445 PMCID: PMC5053858

Turabian/Chicago Citation

Jessica S. Merlin, Hailey W. Bulls, Lee A. Vucovich, E. Jennifer Edelman and Joanna L. Starrels. 2016-12. "Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review." AIDS care 28: 12: 1506-1515. 10.1080/09540121.2016.1191612.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1080/09540121.2016.1191612 | issn = 1360-0451 | volume = 28 | pages = 1506-1515 | last = Merlin | first = Jessica S. | coauthors = Bulls, Hailey W., Vucovich, Lee A., Edelman, E. Jennifer, Starrels, Joanna L. | title = Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review | journal = AIDS care | date = 2016-12 | pmid = | pmc = }} </ref>