Prevalence of low bone mineral density in a low-income inner-city population
Language: 
English
Abstract: 

Bone mineral density (BMD) is an important factor linked to bone health. Little is known of the prevalence of low BMD and its associated risk factors in an urban underserved population. Between 2001 and 2004, we recruited 338 subjects who completed drug use and medical history questionnaires, underwent hormonal measurements, and underwent whole-body dual-energy X-ray absorptiometry (DXA) for evaluation of BMD and body composition. Of these, 132 subjects had site-specific DXA (lumbar spine and hip) performed. Osteoporosis was defined as a T-score of -2.5 or less for men 50 years of age and older and postmenopausal women and a Z-score of -2.0 or less in men younger than 50 years of age and premenopausal women at either the lumbar spine, total hip, or femoral neck, according to National Osteoporosis Foundation (NOF) guidelines. The cohort consisted of mostly African-American, middle-aged people with a high prevalence of illicit drug use, 50% HIV(+), and 39% hepatitis C(+). Osteoporosis was identified in 22% of subjects (24 men, 5 women), with the majority of cases (90%) attributable to osteoporosis at the lumbar spine. Osteoporosis was more common in men than in women. Lower whole-body BMD among women was associated with multiple risk factors, but only with lower lean mass among men. Osteoporosis was highly prevalent in men, mainly at the spine. The risk factors for bone loss in this population need to be further clarified. Screening men for osteoporosis starting at age 50 might be warranted in this population given the multiple risk factors and the unexpectedly high prevalence of low BMD.

Author(s): 
El-Maouche, Diala
Xu, Xiaoqiang
Cofrancesco, Joseph
Dobs, Adrian S.
Brown, Todd T.
Item Type: 
Journal Article
Publication Title: 
Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research
Journal Abbreviation: 
J. Bone Miner. Res.
Publication Date: 
Feb 2011
Publication Year: 
2011
Pages: 
388-396
Volume: 
26
Issue: 
2
ISSN: 
1523-4681
DOI: 
10.1002/jbmr.221
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 20721937 PMCID: PMC3179342

Turabian/Chicago Citation

Diala El-Maouche, Xiaoqiang Xu, Joseph Cofrancesco, Adrian S. Dobs and Todd T. Brown. Feb 2011. "Prevalence of low bone mineral density in a low-income inner-city population." Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research 26: 2: 388-396. 10.1002/jbmr.221.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1002/jbmr.221 | issn = 1523-4681 | volume = 26 | pages = 388-396 | last = El-Maouche | first = Diala | coauthors = Xu, Xiaoqiang, Cofrancesco, Joseph, Dobs, Adrian S., Brown, Todd T. | title = Prevalence of low bone mineral density in a low-income inner-city population | journal = Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research | date = Feb 2011 | pmid = | pmc = }} </ref>