Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol
Language: 
English
Abstract: 

Cardioprotective effect of ethanolic extract of Terminalia chebula fruits (500 mg/kg body wt) was examined in isoproterenol (200 mg/kg body wt) induced myocardial damage in rats. In isoproterenol administered rats, the level of lipid peroxides increased significantly in the serum and heart. A significant decrease was observed in the activity of the myocardial marker enzymes with a concomitant increase in their activity in serum. Histopathological examination was carried out to confirm the myocardial necrosis. T. chebula extract pretreatment was found to ameliorate the effect of isoproterenol on lipid peroxide formation and retained the activities of the diagnostic marker enzymes.

Author(s): 
Suchalatha, S.
Shyamala Devi, C. S.
Item Type: 
Journal Article
Publication Title: 
Indian Journal of Experimental Biology
Journal Abbreviation: 
Indian J. Exp. Biol.
Publication Date: 
2004-02
Publication Year: 
2004
Pages: 
174-178
Volume: 
42
Issue: 
2
ISSN: 
0019-5189
Library Catalog: 
PubMed
Extra: 
PMID: 15282950

Turabian/Chicago Citation

S. Suchalatha and C. S. Shyamala Devi. 2004-02. "Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol." Indian Journal of Experimental Biology 42: 2: 174-178.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0019-5189 | volume = 42 | pages = 174-178 | last = Suchalatha | first = S. | coauthors = Shyamala Devi, C. S. | title = Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol | journal = Indian Journal of Experimental Biology | date = 2004-02 | pmid = | pmc = }} </ref>