Pulmonary tumour with high carcinoembryonic antigen titre caused by chronic propolis aspiration
Language: 
English
Abstract: 

Carcinoembryonic antigen (CEA) titre elevation is sometimes found in benign diseases, such as gastro-intestinal tract inflammatory disease and chronic obstructive pulmonary disease; however, very high CEA titre is rarely encountered in benign pulmonary disease. A 36-yr-old female, who had suffered from body weight loss, was found to have high serum CEA titre (60.8 ng.mL(-1)). Image studies revealed one pulmonary tumour at the left lower lobe, satellite nodules and mediastinal lymphadenopathy. Left lower lobectomy and lymph node dissection were performed for suspicious pulmonary malignancy. The pathological examination revealed that the tumourous lesion was composed of small and fragmented foreign bodies, fibrinopurulent exudate and heavy eosinophils. The bronchial epithelium was characterised by goblet cell hyperplasia and CEA overexpression. The remaining lung parenchyma possessed similar foreign body reaction. The patient's medical history was reviewed and it was found that she had spread propolis topically on nasal mucosa as an adjuvant therapy to asthma for 6 months prior to this medical event. The CEA titre decreased after the operation to 14.2 and 7.88 ng.mL(-1) after 2 weeks and 6 months, respectively. Propolis is used widely in folk medicine but it also has strong sensitising potential. One rare case of propolis aspiration is reported with presentation mimicking lung cancer.

Author(s): 
Lin, W.-C.
Tseng, Y.-T.
Chang, Y.-L.
Lee, Y.-C.
Item Type: 
Journal Article
Publication Title: 
The European Respiratory Journal
Journal Abbreviation: 
Eur. Respir. J.
Publication Date: 
Dec 2007
Publication Year: 
2007
Pages: 
1227-1230
Volume: 
30
Issue: 
6
ISSN: 
0903-1936
DOI: 
10.1183/09031936.00141706
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 18055707

Turabian/Chicago Citation

W.-C. Lin, Y.-T. Tseng, Y.-L. Chang and Y.-C. Lee. Dec 2007. "Pulmonary tumour with high carcinoembryonic antigen titre caused by chronic propolis aspiration." The European Respiratory Journal 30: 6: 1227-1230. 10.1183/09031936.00141706.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1183/09031936.00141706 | issn = 0903-1936 | volume = 30 | pages = 1227-1230 | last = Lin | first = W.-C. | coauthors = Tseng, Y.-T., Chang, Y.-L., Lee, Y.-C. | title = Pulmonary tumour with high carcinoembryonic antigen titre caused by chronic propolis aspiration | journal = The European Respiratory Journal | date = Dec 2007 | pmid = | pmc = }} </ref>