Rebound acid hypersecretion after withdrawal of gastric acid suppressing drugs: new evidence of similitude
Language: 
English
Short Title: 
Rebound acid hypersecretion after withdrawal of gastric acid suppressing drugs
Abstract: 

BACKGROUND: Homeopathy is based on the principle of similitude (similia similibus curentur) using medicines that cause effects similar to the symptoms of disease in order to stimulate the reaction of the organism. Such vital, homeostatic or paradoxical reaction of the organism is closely related to rebound effect of drugs. METHOD: Review of the literature concerning the rebound effects of drugs used to suppress gastric acidity, particularly proton pump inhibitors (PPIs). RESULTS: The mechanism of action of these effects is discussed. Rebound in terms of clinical symptoms and physiological effects occur in about 40% of people taking PPIs, their timing depends on the half-life of the drug and the adaptation period of the physiological mechanisms involved. The wide use of PPIs may be linked to the rising incidence of carcinoid tumours. CONCLUSIONS: These findings support Hahnemann's concept of secondary action of drugs. We are developing a homeopathic materia medica and repertory of modern drugs on the basis of reported rebound effects.

Author(s): 
Teixeira, Marcus Zulian
Item Type: 
Journal Article
Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy
Journal Abbreviation: 
Homeopathy
Publication Date: 
2011-07
Publication Year: 
2011
Pages: 
148-156
Volume: 
100
Issue: 
3
ISSN: 
1476-4245
DOI: 
10.1016/j.homp.2011.05.003
Library Catalog: 
PubMed
Extra: 
PMID: 21784332

Turabian/Chicago Citation

Marcus Zulian Teixeira. 2011-07. "Rebound acid hypersecretion after withdrawal of gastric acid suppressing drugs: new evidence of similitude." Homeopathy: The Journal of the Faculty of Homeopathy 100: 3: 148-156. 10.1016/j.homp.2011.05.003.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.homp.2011.05.003 | issn = 1476-4245 | volume = 100 | pages = 148-156 | last = Teixeira | first = Marcus Zulian | coauthors = | title = Rebound acid hypersecretion after withdrawal of gastric acid suppressing drugs: new evidence of similitude | journal = Homeopathy: The Journal of the Faculty of Homeopathy | date = 2011-07 | pmid = | pmc = }} </ref>