Recuperative effect of Semecarpus anacardium linn. nut milk extract on carbohydrate metabolizing enzymes in experimental mammary carcinoma-bearing rats
Language: 
English
Abstract: 

Semecarpus anacardium Linn. of the family Anacardiaceae has many applications in the Ayurvedic and Siddha systems of medicine. We have tested the antitumour activity of Semecarpus anacardium nut extract against experimental mammary carcinoma in animals. As there is a direct relationship between the proliferation of tumour cells and the activities of the glycolytic and gluconeogenic enzymes, we studied changes in the activities of enzymes involved in this metabolic pathway in the liver and kidney. The enzymes investigated were glycolytic enzymes, namely hexokinase, phosphoglucoisomerase, aldolase and the gluconeogenic enzymes, namely glucose-6-phosphatase and fructose-1,6-biphosphatase in experimental rats. A significant rise in glycolytic enzyme activities and a simultaneous fall in gluconeogenic enzyme activities were found in mammary carcinoma bearing rats. Drug administration returned these enzyme activities to their respective control activities.

Author(s): 
Sujatha, Venugopal
Sachdanandam, Panchanatham
Item Type: 
Journal Article
Publication Title: 
Phytotherapy research: PTR
Journal Abbreviation: 
Phytother Res
Publication Date: 
Mar 2002
Publication Year: 
2002
Pages: 
S14-18
Volume: 
16 Suppl 1
ISSN: 
0951-418X
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 11933133

Turabian/Chicago Citation

Venugopal Sujatha and Panchanatham Sachdanandam. Mar 2002. "Recuperative effect of Semecarpus anacardium linn. nut milk extract on carbohydrate metabolizing enzymes in experimental mammary carcinoma-bearing rats." Phytotherapy research: PTR 16 Suppl 1: S14-18.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0951-418X | volume = 16 Suppl 1 | pages = S14-18 | last = Sujatha | first = Venugopal | coauthors = Sachdanandam, Panchanatham | title = Recuperative effect of Semecarpus anacardium linn. nut milk extract on carbohydrate metabolizing enzymes in experimental mammary carcinoma-bearing rats | journal = Phytotherapy research: PTR | date = Mar 2002 | pmid = | pmc = }} </ref>