Refractory increased intracranial pressure in severe traumatic brain injury: barbiturate coma and bispectral index monitoring
Language: 
English
Short Title: 
Refractory increased intracranial pressure in severe traumatic brain injury
Abstract: 

Patients with severe traumatic brain injury resulting in increased intracranial pressure refractory to first-tier interventions challenge the critical care team. After exhausting these initial interventions, critical care practitioners may utilize barbiturate-induced coma in an attempt to reduce the intracranial pressure. Titrating appropriate levels of barbiturate is imperative. Underdosing the drug may fail to control the intracranial pressure, whereas overdosing may lead to untoward effects such as hypotension and cardiac compromise. Monitoring for a therapeutic level of barbiturate coma includes targeting drug levels and using continuous electroencephalogram monitoring, considered the gold standard. New technology, the Bispectral Index monitor, utilizes electroencephalogram principles to monitor the level of sedation and hypnosis in the critical care environment. This technology is now being considered for targeting appropriate levels of barbiturate coma.

Author(s): 
Bader, Mary Kay
Arbour, Richard
Palmer, Sylvain
Item Type: 
Journal Article
Publication Title: 
AACN clinical issues
Journal Abbreviation: 
AACN Clin Issues
Publication Date: 
2005-12
Publication Year: 
2005
Pages: 
526-541
Volume: 
16
Issue: 
4
ISSN: 
1079-0713
Library Catalog: 
PubMed
Extra: 
PMID: 16269897

Turabian/Chicago Citation

Mary Kay Bader, Richard Arbour and Sylvain Palmer. 2005-12. "Refractory increased intracranial pressure in severe traumatic brain injury: barbiturate coma and bispectral index monitoring." AACN clinical issues 16: 4: 526-541.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 1079-0713 | volume = 16 | pages = 526-541 | last = Bader | first = Mary Kay | coauthors = Arbour, Richard, Palmer, Sylvain | title = Refractory increased intracranial pressure in severe traumatic brain injury: barbiturate coma and bispectral index monitoring | journal = AACN clinical issues | date = 2005-12 | pmid = | pmc = }} </ref>