The role of dietary protein in optimizing muscle mass, function and health outcomes in older individuals
Language: 
English
Abstract: 

The determination of whether increased dietary protein can positively affect health outcomes is hindered by the absence of prospective, randomized trials directly addressing this issue in which all pertinent variables are controlled. Consequently, we can only address the question deductively by considering the support for the rationale underlying the notion of a beneficial effect of increased dietary protein intake. With regard to health outcomes, we have focused on older individuals. Muscle mass and function are progressively lost with aging, so that by the age of 60 many individuals have reached a threshold where function begins to be affected. An association between reduced muscle mass and strength and unfavourable health outcomes is more likely to be revealed in individuals who have significant decrements in muscle mass and strength. In this article support for the rationale underlying the notion of a beneficial effect of increased dietary protein intake is considered. Dietary protein intake, and the resulting increased availability of plasma amino acids, stimulates muscle protein synthesis. If all other variables are controlled, increased muscle protein synthesis leads to improved muscle mass, strength and function over time. Increased muscle mass, strength and function are related to improved health outcomes in older individuals. Since adverse effects of reasonable increases in protein intake above the recommended dietary allowance (RDA) of 0∑8 g protein/kg/day have not been reported, it is reasonable to conclude that the optimal protein intake for an older individual is greater than the RDA.

Author(s): 
Wolfe, Robert R.
Item Type: 
Journal Article
Publication Title: 
The British Journal of Nutrition
Journal Abbreviation: 
Br. J. Nutr.
Publication Date: 
2012-08
Publication Year: 
2012
Pages: 
S88-93
Volume: 
108 Suppl 2
ISSN: 
1475-2662
DOI: 
10.1017/S0007114512002590
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 23107552

Turabian/Chicago Citation

Robert R. Wolfe. 2012-08. "The role of dietary protein in optimizing muscle mass, function and health outcomes in older individuals." The British Journal of Nutrition 108 Suppl 2: S88-93. 10.1017/S0007114512002590.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1017/S0007114512002590 | issn = 1475-2662 | volume = 108 Suppl 2 | pages = S88-93 | last = Wolfe | first = Robert R. | coauthors = | title = The role of dietary protein in optimizing muscle mass, function and health outcomes in older individuals | journal = The British Journal of Nutrition | date = 2012-08 | pmid = | pmc = }} </ref>