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Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: The utility of acupuncture in managing osteoarthritis symptoms is uncertain. Trial results are conflicting and previous systematic reviews may have overestimated the benefits of acupuncture. METHODS: Two reviewers independently identified randomized controlled trials (up to May 2014) from multiple electronic sources (including PubMed/Medline, EMBASE, and CENTRAL) and reference lists of relevant articles, extracted data and assessed risk of bias (Cochrane's Risk of Bias tool).

Manyanga, Taru
Froese, Maria
Zarychanski, Ryan
Abou-Setta, Ahmed
Friesen, Carol
Tennenhouse, Michael
Shay, Barbara L.
Publication Title: 
Mediators of Inflammation

Background. Inflammation is often considered to play a crucial role in epilepsy by affecting iron status and metabolism. In this study, we investigated the curative effect of auricular acupuncture and somatic acupuncture on kainic acid- (KA-) induced epilepsy in rats. Methods. We established an epileptic seizure model in rats by KA (12 mg, ip). The 2 Hz electroacupuncture (EA) was applied at auricular and applied at Zusanli and Shangjuxu (ST36-ST37) acupoints for 20 min for 3 days/week for 6 weeks beginning on the day following the KA injection. Results.

Lin, Yi-Wen
Hsieh, Ching-Liang
Publication Title: 
Physical therapy reviews: PTR

BACKGROUND: Wet needling uses hollow-bore needles to deliver corticosteroids, anesthetics, sclerosants, botulinum toxins, or other agents. In contrast, dry needling requires the insertion of thin monofilament needles, as used in the practice of acupuncture, without the use of injectate into muscles, ligaments, tendons, subcutaneous fascia, and scar tissue. Dry needles may also be inserted in the vicinity of peripheral nerves and/or neurovascular bundles in order to manage a variety of neuromusculoskeletal pain syndromes.

Dunning, James
Butts, Raymond
Mourad, Firas
Young, Ian
Flannagan, Sean
Perreault, Thomas
Publication Title: 
BMJ open

INTRODUCTION: The aim of this protocol is to provide the methods used to assess the effectiveness and safety of acupuncture for the treatment of patients with Alzheimer's disease. METHODS AND ANALYSIS: We will search the following electronic databases: The Cochrane Library, PubMed, Medline, Embase, PsycINFO, Chinese Biomedical Literature Database, Chinese Medical Current Contents and China National Knowledge Infrastructure without restriction of language and publication status.

Zhou, Jing
Peng, Weina
Li, Wang
Liu, Zhishun
Publication Title: 
Evidence-Based Complementary and Alternative Medicine: eCAM

The study was conducted to observe the effect of electroacupuncture (EA) on hepatic blood perfusion (HBP) and vascular regulation. We investigated 60 male anesthetized mice under the following 3 conditions: without EA stimulation (control group); EA stimulation at Zusanli (ST36 group); EA stimulation at nonacupoint (NA group) during 30 min. The HBP was measured using the laser speckle perfusion imaging (LSPI). The level of nitric oxide (NO), endothelin-1 (ET-1), and noradrenaline (NE) in liver tissue was detected by biochemical methods. Results were as follows.

Song, Xiao-Jing
Zhang, Dong
Wang, Shu-You
Li, Shun-Yue
Publication Title: 
Evidence-Based Complementary and Alternative Medicine: eCAM

Moxibustion is one of main therapies in traditional Chinese medicine and uses heat stimulation on the body surface from the burning of moxa to release pain or treat diseases. Emerging studies have shown that moxibustion can generate therapeutic effects by activating a series of signaling pathways and neuroendocrine-immune activities. Here we show moxibustion promoted profound macrophage autophagy in experimental Kunming mice, with reduced Akt phosphorylation and activated eIF2α phosphorylation.

Li, Xiaojuan
Guo, Guanhua
Shen, Feng
Kong, Lihong
Liang, Fengxia
Sun, Guojie
Publication Title: 
Medical Science Monitor: International Medical Journal of Experimental and Clinical Research

BACKGROUND: The anti-oxidative and anti-inflammatory activities of electro-acupuncture (EA), a traditional clinical method, are widely accepted, but its mechanisms are not yet well defined. In this study, we investigated the role of extracellular signal-regulated kinases1/2 (ERK1/2) pathways on electro-acupuncture - mediated up-regulation of heme oxygenase-1 (HO-1) in rabbit lungs injured by LPS-induced endotoxic shock. MATERIAL/METHODS: Seventy rabbits were randomly divided into 7 groups: group C, group M, group D, group SEAM, group EAM, group EAMPD, and group PD98059.

Zhang, Yuan
Yu, Jian-Bo
Luo, Xiao-Qing
Gong, Li-Rong
Wang, Man
Cao, Xin-Shun
Dong, Shu-An
Yan, Yu-Miao
Kwon, Yihyun
He, Jia
Publication Title: 
BioMed Research International

Nowadays, obesity becomes a serious global problem, which can induce a series of diseases such as type 2 diabetes mellitus, cancer, cardiovascular disease, metabolic syndrome, and stoke. For the mechanisms of diseases, the hedgehog signaling pathway plays an important role in body patterning during embryogenesis. For this reason, smoothened homologue (Smo) protein had been indicated as the drug target. In addition, the small-molecule Smo inhibitor had also been used in oncology clinical trials.

Chen, Kuan-Chung
Sun, Mao-Feng
Chen, Hsin-Yi
Lee, Cheng-Chun
Chen, Calvin Yu-Chian
Publication Title: 
Evidence-Based Complementary and Alternative Medicine: eCAM

Hypertension is one of the major risk factors for cardiovascular disease worldwide. Over 70% of the patients use antihypertensive drugs, so nonpharmacological treatments in addition to the medication are important. Our goal was to investigate acupuncture treatment on the Quchi acupoint using heart rate (HR) and heart rate variability (HRV) and to find out whether there is a laterality in acute effects.

Litscher, Gerhard
Cheng, Wei-Ping
Cheng, Guang-Yu
Wang, Lu
Zhao, Jian
Litscher, Daniela
Gaischek, Ingrid
Sheng, Zemin
Kuang, Haixue
Publication Title: 
International Journal of Endocrinology

Objective. This study aimed to evaluate the association between serum uric acid (SUA) levels within a normal to high range and the risk of metabolic syndrome (MetS) among community elderly and explore the sex difference. Design and Methods. A cross-sectional study was conducted in a representative urban area of Beijing between 2009 and 2010. A two-stage stratified clustering sampling method was used and 2102 elderly participants were included. Results. The prevalence of hyperuricemia and MetS was 16.7% and 59.1%, respectively.

Liu, Miao
He, Yao
Jiang, Bin
Wu, Lei
Yang, Shanshan
Wang, Yiyan
Li, Xiaoying