Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs
Language: 
English
Short Title: 
Standardised mindfulness-based interventions in healthcare
Abstract: 

BACKGROUND: Mindfulness-based therapies are being used in a wide range of common chronic conditions in both treatment and prevention despite lack of consensus about their effectiveness in different patient categories. OBJECTIVE: To systematically review the evidence of effectiveness MBSR and MBCT in different patient categories. METHODS: A systematic review and meta-analysis of systematic reviews of RCTs, using the standardized MBSR or MBCT programs. We used PRISMA guidelines to assess the quality of the included reviews and performed a random effects meta-analysis with main outcome measure Cohen's d. All types of participants were considered. RESULTS: The search produced 187 reviews: 23 were included, covering 115 unique RCTs and 8,683 unique individuals with various conditions. Compared to wait list control and compared to treatment as usual, MBSR and MBCT significantly improved depressive symptoms (d=0.37; 95%CI 0.28 to 0.45, based on 5 reviews, N=2814), anxiety (d=0.49; 95%CI 0.37 to 0.61, based on 4 reviews, N=2525), stress (d=0.51; 95%CI 0.36 to 0.67, based on 2 reviews, N=1570), quality of life (d=0.39; 95%CI 0.08 to 0.70, based on 2 reviews, N=511) and physical functioning (d=0.27; 95%CI 0.12 to 0.42, based on 3 reviews, N=1015). Limitations include heterogeneity within patient categories, risk of publication bias and limited long-term follow-up in several studies. CONCLUSION: The evidence supports the use of MBSR and MBCT to alleviate symptoms, both mental and physical, in the adjunct treatment of cancer, cardiovascular disease, chronic pain, depression, anxiety disorders and in prevention in healthy adults and children.

Author(s): 
Gotink, Rinske A.
Chu, Paula
Busschbach, Jan J. V.
Benson, Herbert
Fricchione, Gregory L.
Hunink, M. G. Myriam
Item Type: 
Journal Article
Publication Title: 
PloS One
Journal Abbreviation: 
PLoS ONE
Publication Date: 
2015
Publication Year: 
2015
Pages: 
e0124344
Volume: 
10
Issue: 
4
ISSN: 
1932-6203
DOI: 
10.1371/journal.pone.0124344
Library Catalog: 
PubMed
Extra: 
PMID: 25881019 PMCID: PMC4400080

Turabian/Chicago Citation

Rinske A. Gotink, Paula Chu, Jan J. V. Busschbach, Herbert Benson, Gregory L. Fricchione and M. G. Myriam Hunink. 2015. "Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs." PloS One 10: 4: e0124344. 10.1371/journal.pone.0124344.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1371/journal.pone.0124344 | issn = 1932-6203 | volume = 10 | pages = e0124344 | last = Gotink | first = Rinske A. | coauthors = Chu, Paula, Busschbach, Jan J. V., Benson, Herbert, Fricchione, Gregory L., Hunink, M. G. Myriam | title = Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs | journal = PloS One | date = 2015 | pmid = | pmc = }} </ref>