Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake
Language: 
English
Abstract: 

Post-traumatic stress disorder (PTSD) widely occurs among victims or witness of disasters. With flashbacks, hyperarousal, and avoidance being the typical symptoms, PTSD became a focus of psychological research. The earthquake in Wenchuan, China, on May 12, 2008, was without precedent in magnitude and aftermath and caused huge damage, which drew scientists' attention to mental health of the survivors. We conducted a systematic overview by collecting published articles from the PubMed database and classifying them into five points: epidemiology, neuropathology, biochemistry, genetics and epigenetics, and treatment. The large body of research during the past 6 years showed that adolescents and adults were among the most studied populations with high prevalence rates for PTSD. Genomic and transcriptomic studies focusing on gene × environment studies as well as epigenetics are still rare, although a few available data showed great potential to better understand the pathophysiology of PTSD as multifactorial disease. Phytotherapy with Chinese herbs and acupuncture are rarely reported as of yet, although the first published data indicated promising therapy effects. Future studies should focus on the following points: (1) The affected populations under observation should be better defined concerning individual risk factor, time of observation, spatial movement, and individual disease courses of patients. (2) The role of social support for prevalence rates of PTSD should be observed in more detail. (3) Efficacy and safety of Chinese medicine should be studied to find potential interventions and effective treatments of PTSD.

Author(s): 
Hong, Chunlan
Efferth, Thomas
Item Type: 
Journal Article
Publication Title: 
Trauma, Violence & Abuse
Journal Abbreviation: 
Trauma Violence Abuse
Publication Date: 
2016-12
Publication Year: 
2016
Pages: 
542-561
Volume: 
17
Issue: 
5
ISSN: 
1552-8324
DOI: 
10.1177/1524838015585313
Library Catalog: 
PubMed
Extra: 
PMID: 26028651

Turabian/Chicago Citation

Chunlan Hong and Thomas Efferth. 2016-12. "Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake." Trauma, Violence & Abuse 17: 5: 542-561. 10.1177/1524838015585313.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1177/1524838015585313 | issn = 1552-8324 | volume = 17 | pages = 542-561 | last = Hong | first = Chunlan | coauthors = Efferth, Thomas | title = Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake | journal = Trauma, Violence & Abuse | date = 2016-12 | pmid = | pmc = }} </ref>