Tegument changes of Schistosoma japonicum and Schistosoma mansoni in mice treated with artemether
Language: 
English
Abstract: 

AIM: To study the effect of artemether (Art) on the tegument of schistosomes. METHODS: Mice infected with S japonicum cercariae for 7 and 35 d, or with S mansoni cercariae for 49 d were treated intragastrically with Art 200-300 mg.kg-1.d-1 for 2 d. Schistosomes were collected in groups of 2 mice at various intervals after medication for scanning electron microscopic observation. RESULTS: The tegumental changes induced by Art appeared to be similar in S japonicum and S mansoni: swelling and fusion of tegumental surfaces, vesicle formation and collapse of discoid-like sensory structures. In S japonicum the emergence of tegumental alterations was earlier in 7-d-old schistosomulae than that in 35-d-old adult worms. CONCLUSION: Art injured the teguments of S japonicum and S mansoni.

Author(s): 
Xiao, S. H.
Shen, B. G.
Horner, J.
Catto, B. A.
Item Type: 
Journal Article
Publication Title: 
Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica
Journal Abbreviation: 
Zhongguo Yao Li Xue Bao
Publication Date: 
Nov-96
Publication Year: 
1996
Pages: 
535-537
Volume: 
17
Issue: 
6
ISSN: 
0253-9756
Library Catalog: 
PubMed
Extra: 
PMID: 9863150

Turabian/Chicago Citation

S. H. Xiao, B. G. Shen, J. Horner and B. A. Catto. Nov-96. "Tegument changes of Schistosoma japonicum and Schistosoma mansoni in mice treated with artemether." Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica 17: 6: 535-537.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0253-9756 | volume = 17 | pages = 535-537 | last = Xiao | first = S. H. | coauthors = Shen, B. G., Horner, J., Catto, B. A. | title = Tegument changes of Schistosoma japonicum and Schistosoma mansoni in mice treated with artemether | journal = Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica | date = Nov-96 | pmid = | pmc = }} </ref>