Tel-1 transposon-like elements of Tetrahymena thermophila are associated with micronuclear genome rearrangements
Language: 
English
Abstract: 

The micronuclear genome of Tetrahymena thermophila contains Tel-1 elements that structurally resemble transposons. Here we present molecular evidence that Tel-1 transposon-like elements are mobile. The arrangements of Tel-1 elements in the micronuclear genomes of several T. thermophila strains and cell lines were assayed by Southern blotting. The molecular evidence for Tel-1 transposition is most striking in strains that have undergone unusual laboratory-induced meioses. The genetic history of the strains exhibiting evidence of Tel-1 transposition is consistent with periods of genome restructuring in response to genomic "shock" that B. McClintock has suggested could result in transposon activation.

Author(s): 
Wyman, C.
Blackburn, E. H.
Item Type: 
Journal Article
Publication Title: 
Genetics
Journal Abbreviation: 
Genetics
Publication Date: 
1991-09
Publication Year: 
1991
Pages: 
57-67
Volume: 
129
Issue: 
1
ISSN: 
0016-6731
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 1657703 PMCID: PMC1204581

Turabian/Chicago Citation

C. Wyman and E. H. Blackburn. 1991-09. "Tel-1 transposon-like elements of Tetrahymena thermophila are associated with micronuclear genome rearrangements." Genetics 129: 1: 57-67.

Wikipedia Citation

<ref> {{Cite journal | doi = | issn = 0016-6731 | volume = 129 | pages = 57-67 | last = Wyman | first = C. | coauthors = Blackburn, E. H. | title = Tel-1 transposon-like elements of Tetrahymena thermophila are associated with micronuclear genome rearrangements | journal = Genetics | date = 1991-09 | pmid = | pmc = }} </ref>