Traditional Chinese medicine for chronic fatigue syndrome: a systematic review of randomized clinical trials
Language: 
English
Short Title: 
Traditional Chinese medicine for chronic fatigue syndrome
Abstract: 

BACKGROUND: There is no curative treatment for chronic fatigue syndrome (CFS). Traditional Chinese medicine (TCM) is widely used in the treatment of CFS in China. OBJECTIVE: To evaluate the effectiveness and safety of TCM for CFS. METHODS: The protocol of this review is registered at PROSPERO. We searched six main databases for randomized clinical trials (RCTs) on TCM for CFS from their inception to September 2013. The Cochrane risk of bias tool was used to assess the methodological quality. We used RevMan 5.1 to synthesize the results. RESULTS: 23 RCTs involving 1776 participants were identified. The risk of bias of the included studies was high. The types of TCM interventions varied, including Chinese herbal medicine, acupuncture, qigong, moxibustion, and acupoint application. The results of meta-analyses and several individual studies showed that TCM alone or in combination with other interventions significantly alleviated fatigue symptoms as measured by Chalder's fatigue scale, fatigue severity scale, fatigue assessment instrument by Joseph E. Schwartz, Bell's fatigue scale, and guiding principle of clinical research on new drugs of TCM for fatigue symptom. There was no enough evidence that TCM could improve the quality of life for CFS patients. The included studies did not report serious adverse events. CONCLUSIONS: TCM appears to be effective to alleviate the fatigue symptom for people with CFS. However, due to the high risk of bias of the included studies, larger, well-designed studies are needed to confirm the potential benefit in the future.

Author(s): 
Wang, Yu-Yi
Li, Xin-Xue
Liu, Jian-Ping
Luo, Hui
Ma, Li-Xin
Alraek, Terje
Item Type: 
Journal Article
Publication Title: 
Complementary Therapies in Medicine
Journal Abbreviation: 
Complement Ther Med
Publication Date: 
2014-08
Publication Year: 
2014
Pages: 
826-833
Volume: 
22
Issue: 
4
ISSN: 
1873-6963
DOI: 
10.1016/j.ctim.2014.06.004
Library Catalog: 
PubMed
Extra: 
PMID: 25146086

Turabian/Chicago Citation

Yu-Yi Wang, Xin-Xue Li, Jian-Ping Liu, Hui Luo, Li-Xin Ma and Terje Alraek. 2014-08. "Traditional Chinese medicine for chronic fatigue syndrome: a systematic review of randomized clinical trials." Complementary Therapies in Medicine 22: 4: 826-833. 10.1016/j.ctim.2014.06.004.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1016/j.ctim.2014.06.004 | issn = 1873-6963 | volume = 22 | pages = 826-833 | last = Wang | first = Yu-Yi | coauthors = Li, Xin-Xue, Liu, Jian-Ping, Luo, Hui, Ma, Li-Xin, Alraek, Terje | title = Traditional Chinese medicine for chronic fatigue syndrome: a systematic review of randomized clinical trials | journal = Complementary Therapies in Medicine | date = 2014-08 | pmid = | pmc = }} </ref>