Publication Title: 
Journal of Environmental Pathology, Toxicology and Oncology: Official Organ of the International Society for Environmental Toxicology and Cancer

We report the results of our genotoxic evaluation of extracts from three medicinal plants Acacia nilotica, Juglans regia, and Terminalia chebula and the herbal drug Triphala employing the VITOTOX and comet tests.These tests detect DNA damage in prokaryotic and eukaryotic test systems, respectively. In the VITOTOX test, none of the extracts were identified as genotoxic.

Arora, Saroj
Brits, Ethel
Kaur, Swayamjot
Kaur, Kamaljeet
Sohi, Rajbir S.
Kumar, Subodh
Verschaeve, Luc
Publication Title: 

The current study was aimed to evaluate Acacia modesta for analgesic, anti-inflammatory, and anti-platelet activities. The analgesic and anti-inflammatory effects were assessed in rodents using acetic acid and formalin-induced nociception, hot plate and carrageenan-induced rat paw oedema tests. The intraperitoneal (i.p.) administration of the methanolic extract (50 and 100 mg/kg) produced significant inhibition (P\0.01) of the acetic acid-induced writhing in mice and suppressed formalin-induced licking response of animals in both phases of the test.

Bukhari, Ishfaq A.
Khan, Rafeeq A.
Gilani, Anwar H.
Ahmed, Sagheer
Saeed, Sheikh Arshad
Publication Title: 
Journal of AOAC International

A sensitive, simple, rapid, and efficient HPTLC method was developed and validated for the analysis of catechin in marketed Ayurvedic oil formulations containing Acacia catechu. Chromatography of methanolic-0.1% formic acid (7:3, v/v) extracts of these formulations was performed on silica gel 60 F254 aluminum-backed TLC plates of 0.2 mm layer thickness. The plate was developed up to 85 mm with the ternary-mobile phase chloroform-acetone-0.1% formic acid (7.7 + 1.5 + 0.8%, v/v/v) at 22 +/- 2 degrees C with 20 min of chamber saturation.

Dubey, Nidhi
Dubey, Nitin
Mehta, Rajendra
Saluja, Ajay
Publication Title: 
Annals of Hepatology

The case of a 64 year old female patient is presented who has treated herself for 9 months with various Indian Ayurvedic herbal products for her vitiligo and experienced a causally related severe hepatotoxicity (ALT, 601 U/L; AST, 663 U/L; Bilirubin, 5.0 mg/dL). After discontinuation, a rapid improvement was observed.

Teschke, Rolf
Bahre, Ruediger
Subscribe to RSS - Acacia