Adrenalectomy

Publication Title: 
The Journal of Pharmacology and Experimental Therapeutics

The relationship between circadian rhythms in the pharmacological actions of meperidine and hexobarbital and similar rhythms in the hepatic metabolism of these drugs was examined in mice under a variety of environmental alterations to determine whether such rhythms may be causally related. The rate of metabolism of p-nitroanisole and hexobarbital by hepatic 9000 X g supernatant fractions was found to be higher at 2400 hours (middark phase) compared to 1200 hours (midlight phase).

Author(s): 
Holcslaw, T. L.
Miya, T. S.
Bousquet, W. S.
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Electroacupuncture (EA) has been reported to produce anti-edema and anti-hyperalgesia effects on inflammatory disease. However, the mechanisms are not clear. The present study investigated the biochemical mechanisms of EA anti-inflammation in a rat model. METHODS: Three experiments were conducted on male Sprague-Dawley rats (n = 7-8/per group). Inflammation was induced by injecting complete Freund's adjuvant (CFA) subcutaneously into the plantar surface of one hind paw. Experiment 1 measured plasma corticosterone (CORT) levels to see if EA regulates CORT secretion.

Author(s): 
Li, Aihui
Zhang, Rui-Xin
Wang, Yi
Zhang, Haiqing
Ren, Ke
Berman, Brian M.
Tan, Ming
Lao, Lixing
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Electroacupuncture (EA) has been reported to produce anti-edema and anti-hyperalgesia effects on inflammatory disease. However, the mechanisms are not clear. The present study investigated the biochemical mechanisms of EA anti-inflammation in a rat model. METHODS: Three experiments were conducted on male Sprague-Dawley rats (n = 7-8/per group). Inflammation was induced by injecting complete Freund's adjuvant (CFA) subcutaneously into the plantar surface of one hind paw. Experiment 1 measured plasma corticosterone (CORT) levels to see if EA regulates CORT secretion.

Author(s): 
Li, Aihui
Zhang, Rui-Xin
Wang, Yi
Zhang, Haiqing
Ren, Ke
Berman, Brian M.
Tan, Ming
Lao, Lixing
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