alternative promoters

Publication Title: 
The Yale Journal of Biology and Medicine

The BDNF is required for the development and proper function of the central nervous system, where it is involved in a variety of neural and molecular events relevant to cognition, learning, and memory processes. Although only a functional mature protein is synthesized, the human BDNF gene possesses an extensive structural complexity, including the presence of multiple promoters, splicing events, and 3¥UTR poly-adenylation sites, resulting in an intricate transcriptional regulation and numerous messengers RNA. Recent data support specific cellular roles of these transcripts.

MartÌnez-Levy, Gabriela A.
Cruz-Fuentes, Carlos S.
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