Anemia

Publication Title: 
Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]
Author(s): 
Wang, X. Y.
Publication Title: 
Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]

OBJECTIVE: To describe the epidemiological characteristics of anemia among elderly people aged 80 years old and above in longevity areas in China and to analyze its relevant factors to the health effects. METHODS: The data used in this study came from the Chinese Longitudinal Healthy Longevity Survey, including all centenarians in 7 longevity areas, as well as randomly selected population aged 40-, 60-, 80- and 90- in the same 7 areas. A total of 1980 subjects enrolled in the study. The data of general information, eating habits and diseases history was collected by questionnaire survey.

Author(s): 
Zhai, Yi
Yin, Zhao-Xue
Xu, Jian-Wei
Zeng, Yi
Liu, Yu-Zhi
Shi, Xiao-Ming
Publication Title: 
The Practitioner
Author(s): 
Blackburn, E. K.
Publication Title: 
Developments in Biologicals

Phlebotomy of a unit of blood produces a loss of 200 to 250 mg of iron in haemoglobin. Because of physiological differences in iron balance between women of childbearing age and men, the loss of similar amounts of iron at donation has divergent consequences for committed donors. Women of childbearing age have an increased risk of iron deficiency if they donate more than one unit per year while men are usually able to maintain iron balance while donating four or more units of blood per year.

Author(s): 
Brittenham, G. M.
Publication Title: 
The Journal of Infectious Diseases

BACKGROUND: There is no safe, practical, and effective treatment for pregnant women infected with multidrug-resistant Plasmodium falciparum. METHODS: We recruited pregnant Karen women in the second or third trimesters of pregnancy who had uncomplicated falciparum malaria for a randomized, open-label trial with a restricted sequential trial design of 7 days of supervised quinine (SQ7) versus 3 days of artesunate-atovaquone-proguanil (AAP). RESULTS: Eight-one pregnant women entered the study between December 2001 and July 2003; 42 were treated with SQ7 and 39 were treated with AAP.

Author(s): 
McGready, Rose
Ashley, Elizabeth A.
Moo, Eh
Cho, Thein
Barends, Marion
Hutagalung, Robert
Looareesuwan, Sornchai
White, Nicholas J.
Nosten, François
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

A community-based baseline cross-sectional survey was conducted in three districts in Togo in September 2004 as part of a multidisciplinary evaluation of the impact of the Togo National Integrated Child Health Campaign. During this campaign, long-lasting-insecticide-treated bed nets (LLITNs) were distributed to households with children between 9 months and 5 years of age throughout the country in December 2004. The pre-intervention survey provided baseline malaria and anemia prevalence in children < 5 years of age during peak malaria transmission.

Author(s): 
Eliades, M. James
Wolkon, Adam
Morgah, Kodjo
Crawford, Sara B.
Dorkenoo, Ameyo
Sodahlon, Yao
Hawley, William A.
Hightower, Allen W.
Kuile, Feiko O. Ter
Terlouw, Dianne J.
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

The choice of artemisinin-based combination that is being adopted for malaria treatment in sub-Saharan Africa may depend on several factors, including cost, efficacy, side effects, and simplicity of administration. We tested the hypothesis that artesunate-sulfamethoxypyrazine-pyrimethamine is as efficacious as the four-dose regimen of artemether-lumefantrine for treatment of Plasmodium falciparum malaria. The study was carried out during two transmission seasons (2003 and 2004) in Sotuba, Mali. Participants at least 6 months of age with uncomplicated P.

Author(s): 
Sagara, Issaka
Dicko, Alassane
Djimde, Abdoulaye
Guindo, Ousmane
Kone, Mamady
Tolo, Youssouf
Thera, Mahamadou A.
Sogoba, Moussa
Fofana, Moussa
Ouattara, Amed
Sissoko, Mady
Jansen, Herwig F.
Doumbo, Ogobara K.
Publication Title: 
Tropical medicine & international health: TM & IH

OBJECTIVES: To compare the efficacy and tolerability of dihydroartemisinin-piperaquine (DHA-PQP) with that of a 3-day regimen of mefloquine and artesunate (MAS3) for the treatment of uncomplicated falciparum malaria in Cambodia. METHOD: Randomized open-label non-inferiority study over 64 days. RESULTS: Four hundred and sixty-four patients were included in the study. The polymerase chain reaction genotyping-adjusted cure rates on day 63 were 97.5% (95% confidence interval, CI, 93.8-99.3) for DHA-PQP and 97.5% (95% CI, 93.8-99.3) for MAS3, P = 1.

Author(s): 
Janssens, B.
van Herp, M.
Goubert, L.
Chan, S.
Uong, S.
Nong, S.
Socheat, D.
Brockman, A.
Ashley, E. A.
Van Damme, W.
Publication Title: 
Lancet (London, England)

BACKGROUND: The burden of Plasmodium vivax infections has been underappreciated, especially in southeast Asia where chloroquine resistant strains have emerged. Our aim was to compare the safety and efficacy of dihydroartemisinin-piperaquine with that of artemether-lumefantrine in patients with uncomplicated malaria caused by multidrug-resistant P falciparum and P vivax. METHODS: 774 patients in southern Papua, Indonesia, with slide-confirmed malaria were randomly assigned to receive either artemether-lumefantrine or dihydroartemisinin-piperaquine and followed up for at least 42 days.

Author(s): 
Ratcliff, A.
Siswantoro, H.
Kenangalem, E.
Maristela, R.
Wuwung, R. M.
Laihad, F.
Ebsworth, E. P.
Anstey, N. M.
Tjitra, E.
Price, R. N.
Publication Title: 
Malaria Journal

BACKGROUND: Benin has recently shifted its national antimalarial drug policy from monotherapies to combinations containing artemisinin derivatives. When this decision was taken, the available information on alternatives to chloroquine and sulphadoxine-pyrimethamine, the first- and second-line treatment, was sparse.

Author(s): 
Nahum, Alain
Erhart, Annette
Gazard, Dorothée
Agbowai, Carine
Van Overmeir, Chantal
van Loen, Harry
Menten, Joris
Akogbeto, Martin
Coosemans, Marc
Massougbodji, Achille
D'Alessandro, Umberto

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