Anti-Allergic Agents

Publication Title: 
Otolaryngology--Head and Neck Surgery: Official Journal of American Academy of Otolaryngology-Head and Neck Surgery

OBJECTIVE: Allergic rhinitis (AR) is one of the most common diseases affecting adults. It is the most common chronic disease in children in the United States today and the fifth most common chronic disease in the United States overall. AR is estimated to affect nearly 1 in every 6 Americans and generates $2 to $5 billion in direct health expenditures annually. It can impair quality of life and, through loss of work and school attendance, is responsible for as much as $2 to $4 billion in lost productivity annually.

Author(s): 
Seidman, Michael D.
Gurgel, Richard K.
Lin, Sandra Y.
Schwartz, Seth R.
Baroody, Fuad M.
Bonner, James R.
Dawson, Douglas E.
Dykewicz, Mark S.
Hackell, Jesse M.
Han, Joseph K.
Ishman, Stacey L.
Krouse, Helene J.
Malekzadeh, Sonya
Mims, James Whit W.
Omole, Folashade S.
Reddy, William D.
Wallace, Dana V.
Walsh, Sandra A.
Warren, Barbara E.
Wilson, Meghan N.
Nnacheta, Lorraine C.
Guideline Otolaryngology Development Group. AAO-HNSF
Publication Title: 
Journal of Biosciences

Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance with ginger but imparts a raw mango flavour. The main use of mango ginger rhizome is in the manufacture of pickles and culinary preparations. Ayurveda and Unani medicinal systems have given much importance to mango ginger as an appetizer, alexteric, antipyretic, aphrodisiac, diuretic, emollient, expectorant and laxative and to cure biliousness, itching, skin diseases, bronchitis, asthma, hiccough and inflammation due to injuries.

Author(s): 
Policegoudra, R. S.
Aradhya, S. M.
Singh, L.
Publication Title: 
Journal of Medicinal Food

Allium cepa (Family Liliaceae) is a reputed Indian medicinal herb that is prescribed as an effective remedy for several ailments in the Ayurvedic system of medicine. The aim of this study was to evaluate its efficacy against various events responsible for Type I allergic reactions. A herbal fraction (ALC-02) from A. cepa (bulb) inhibited histamine release and attenuated intracellular calcium levels in Compound 48/80-induced rat peritoneal mast cells. It also prevented Compound 48/80-mediated systemic anaphylaxis while lowering histamine levels in plasma.

Author(s): 
Kaiser, P.
Youssouf, M. S.
Tasduq, S. A.
Singh, S.
Sharma, S. C.
Singh, G. D.
Gupta, V. K.
Gupta, B. D.
Johri, R. K.
Publication Title: 
Journal of Biosciences

Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance with ginger but imparts a raw mango flavour. The main use of mango ginger rhizome is in the manufacture of pickles and culinary preparations. Ayurveda and Unani medicinal systems have given much importance to mango ginger as an appetizer, alexteric, antipyretic, aphrodisiac, diuretic, emollient, expectorant and laxative and to cure biliousness, itching, skin diseases, bronchitis, asthma, hiccough and inflammation due to injuries.

Author(s): 
Policegoudra, R. S.
Aradhya, S. M.
Singh, L.
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

Allergy is an acquired hypersensitivity reaction of the immune system mediated by cross-linking of the allergen-specific IgE-bound high-affinity IgE receptors, leading to immediate mast cell degranulation. Rottlerin is an active molecule isolated from Mallotus philippinensis, a medicinal plant used in Ayurvedic Medicine System for anti-allergic and anti-helminthic treatments. The present study investigated potential anti-allergic effects of rottlerin in animal models of IgE-dependent anaphylaxis and the anti-allergic mechanisms of action of rottlerin in mast cells.

Author(s): 
Chan, Tze Khee
Ng, David S. W.
Cheng, Chang
Guan, Shou Ping
Koh, Hock Meng
Wong, W. S. Fred
Publication Title: 
The Journal of Allergy and Clinical Immunology

The increasing prevalence of allergic diseases in Westernized countries is a significant health problem. Curative therapies for these diseases are not available. There are also significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children. Many patients with chronic allergic conditions seek complementary and alternative medicine therapies including traditional Chinese medicines.

Author(s): 
Li, Xiu-Min
Publication Title: 
The Journal of Allergy and Clinical Immunology

BACKGROUND: Although corticosteroids and beta(2)-agonists are effective in managing asthma symptoms, a curative therapy for asthma is lacking. Traditional Chinese medicine (TCM), used in Asia for centuries, is beginning to play a role in Western health care as a complementary and alternative medicine modality. There is increasing scientific evidence supporting the use of TCM for asthma treatment. OBJECTIVE: This review article discusses promising TCM interventions for asthma and explores their possible mechanisms of action.

Author(s): 
Li, Xiu-Min
Brown, Laverne
Publication Title: 
Burns: Journal of the International Society for Burn Injuries

Post-burn itch is a distressing symptom in burns rehabilitation and its treatment often proves frustrating for the patient and the multidisciplinary burns team. Traditionally, the mainstay of antipruritic therapy for decades has been antihistamines and massage with emollients. With a better understanding of the neurophysiology of itch emerged a new dimension in the treatment of post-burn pruritus. Gabapentin, a centrally modulating anti-epileptic agent and α2δ ligand, proved in clinical trials to be immensely better in the treatment of post-burn pruritus.

Author(s): 
Ahuja, Rajeev B.
Gupta, Gaurav K.
Publication Title: 
Alternative Medicine Review: A Journal of Clinical Therapeutic

There are conceptual and historical links between homeopathic medicine and modern allergy desensitization treatment. Conventional allergy desensitization and homeopathic treatment both utilize small doses of substances that might cause symptoms in order to prevent or treat a hypersensitive state. Homeopathy has historically been associated with allergy treatment. This article reviews evidence from controlled trials for the use of homeopathy in respiratory allergies.

Author(s): 
Ullman, Dana
Frass, Michael
Publication Title: 
Wiener Klinische Wochenschrift

OBJECTIVE: The prevalence of allergic disorders in western industrialized countries has steadily increased during the last three decades. Public acceptance of complementary treatment methods is high. The aim of this study was to assess the real-life efficacy of classical homeopathic treatment and the potential to reduce conventional medication dosage. METHODS: A prospective multicenter observational study was conducted by general practitioners specializing in homeopathy in nine Austrian test centers.

Author(s): 
Gründling, Christa
Schimetta, Wolfgang
Frass, Michael

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