Antivenins

Publication Title: 
Toxicon: Official Journal of the International Society on Toxinology

American Elapid snakes (Coral Snakes) comprise the genera Leptomicrurus, Micruroides and Micrurus, which form a vast taxonomic assembly of 330 species distributed from the South of United States to the southern region of South America. In order to obtain venom for animal immunizations aimed at antivenom production, Coral Snakes must be kept in captivity and submitted periodically to venom extraction procedures. Thus, to maintain a snake colony in good health for this purpose, a complete alternative diet utilizing an easily obtained prey animal is desirable.

Author(s): 
ChacÛn, Danilo
RodrÌguez, Santos
Arias, JazmÌn
Solano, Gabriela
Bonilla, Fabi·n
GÛmez, AarÛn
Publication Title: 
Journal of Ethnopharmacology

ETHNOPHARMACOLOGICAL RELEVANCE: Although serotherapy against snakebite has been discovered more than one hundred years ago, antivenom is not available all over Brazil. The use of plants from folk medicine is common mainly in the Brazilian Amazon area. One of these plants is named Humirianthera ampla (HA). MATERIALS AND METHODS: We have investigated HA extract and constituents' antiophidic activity in different experimental protocols against some Bothrops snake venoms (Bothrops jararacussu, Bothrops atrox and Bothrops jararaca).

Author(s): 
Strauch, Marcelo Abrahão
Tomaz, Marcelo Amorim
Monteiro-Machado, Marcos
Ricardo, Hilmar Dias
Cons, Bruno Lemos
Fernandes, Fabrício F. A.
El-Kik, Camila Z.
Azevedo, Mariângela Soares
Melo, Paulo A.
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