Aspirin

Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy

Samuel Hahnemann attributed fundamental importance to the principle of similitude, promoting it to a 'natural law'. Observing that enantiopathic or allopathic treatment produced enduring aggravation of the disease symptoms after a brief and transitory initial relief, he systematised homeopathic treatment, prescribing substances that provoke similar symptoms in healthy individual.

Author(s): 
Teixeira, M. Z.
Publication Title: 
BMJ clinical evidence

INTRODUCTION: Dysmenorrhoea may begin soon after the menarche, after which it often improves with age, or it may originate later in life after the onset of an underlying causative condition. Dysmenorrhoea is common, and in up to 20% of women it may be severe enough to interfere with daily activities. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for primary dysmenorrhoea?

Author(s): 
Latthe, Pallavi Manish
Champaneria, Rita
Khan, Khalid Saeed
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

In continuation of our drug discovery program on Indian medicinal plants, the gastro protective mechanism of chebulinic acid isolated from Terminalia chebula fruit was investigated. Chebulinic acid was evaluated against cold restraint (CRU), aspirin (AS), alcohol (AL) and pyloric ligation (PL) induced gastric ulcer models in rats. Potential anti-ulcer activity of chebulinic acid was observed against CRU (62.9%), AS (55.3%), AL (80.67%) and PL (66.63%) induced ulcer models.

Author(s): 
Mishra, Vaibhav
Agrawal, Manali
Onasanwo, Samuel Adetunji
Madhur, Gaurav
Rastogi, Preeti
Pandey, Haushila Prasad
Palit, Gautam
Narender, Tadigoppula
Publication Title: 
Progress in Neuro-Psychopharmacology & Biological Psychiatry

In many individuals with major neuropsychiatric disorders including depression, bipolar disorder and schizophrenia, their disease characteristics are consistent with a neuroprogressive illness. This includes progressive structural brain changes, cognitive and functional decline, poorer treatment response and an increasing vulnerability to relapse with chronicity.

Author(s): 
Dodd, Seetal
Maes, Michael
Anderson, George
Dean, Olivia M.
Moylan, Steven
Berk, Michael
Publication Title: 
Annals of the New York Academy of Sciences
Author(s): 
Stern, J. A.
Brown, M.
Ulett, G. A.
Sletten, I.
Publication Title: 
Pain

This simple method of achieving substantial pain control in patients with documented herpes zoster and postherpetic neuralgia has been effective in each of the patients in whom it has been used (the most recent 12 cases have been summarized for this report). It has been more effective than narcotic analgesics, oral anti-inflammatory analgesics, sedatives, tranquilizers, TENS, hypnosis and the wide variety of operative measures we have tried in the past.

Author(s): 
King, R. B.
Publication Title: 
Aruk?ru Kenky? to Yakubutsu Izon = Japanese Journal of Alcohol Studies & Drug Dependence

It is known that prostaglandin synthetase inhibitors (PGSI) inhibit ethanol (EtOH)-induced sleep in mice, and that EtOH increases production of prostaglandins (PGs). EtOH hypnosis and effects of prostaglandins on EtOH-induced sleeping in inbred rats were examined. The EtOH (3 g/kg, i.p.)-induced sleep time was significantly longer in Fischer 344 (F344) than in Lewis (LEW); blood EtOH concentrations (BAC) on awaking were significantly lower in F344 than in LEW.

Author(s): 
Suzuki, T.
Shiozaki, Y.
Misawa, M.
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Ayurveda, the Indian traditional system of medicine describes a unique concept "prakriti", genetically determined, categorising the population into several subgroups based on phenotypic characters like appearance, temperament and habits. The concept is claimed to be useful in predicting an individual's susceptibility to a particular disease, prognosis of that illness and selection of therapy. The present study was carried out to study if the platelet aggregatory response and its inhibition by aspirin varied in the different prakriti subtypes.

Author(s): 
Bhalerao, Supriya
Deshpande, Tejashree
Thatte, Urmila
Publication Title: 
Journal of Ethnopharmacology

The widely known tree Abies pindrow (Talisapatra) (family: Pinaceae), famous for its diverse clinical uses in Ayurvedic medicines, was investigated to rationalise some of the ancient claims. The petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanol (EE) extracts of A. pindrow leaf were found to have mast cell stabilizing action in rats. The EE, AE and BE extracts offered bronchoprotection against histamine challenge in guinea-pigs. The BE, CE and PE extracts had protective role in aspirin-induced ulcer in rats.

Author(s): 
Singh, R. K.
Bhattacharya, S. K.
Acharya, S. B.
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

Bacopa monniera Wettst. (BM, syn. Herpestis monniera L; Scrophulariaceae), is an Ayurvedic drug used as a rasayana. Its fresh juice was earlier reported to have significant antiulcerogenic activity. In continuation, methanolic extract of BM (BME) standardized to bacoside-A content (percentage-38.0 +/- 0.9), when given in the dose of 10-50 mg/kg, twice daily for 5 days, showed dose-dependent anti-ulcerogenic on various gastric ulcer models induced by ethanol, aspirin, 2 h cold restraint stress and 4 h pylorus ligation.

Author(s): 
Sairam, K.
Rao, C. V.
Babu, M. D.
Goel, R. K.

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