Asteraceae

Publication Title: 
Malaria Journal

BACKGROUND: Anti-malarial drug resistance threatens to undermine efforts to eliminate this deadly disease. The resulting omnipresent requirement for drugs with novel modes of action prompted a national consortium initiative to discover new anti-plasmodial agents from South African medicinal plants. One of the plants selected for investigation was Dicoma anomala subsp. gerrardii, based on its ethnomedicinal profile.

Author(s): 
Becker, John V. W.
van der Merwe, Marina M.
van Brummelen, Anna C.
Pillay, Pamisha
Crampton, Bridget G.
Mmutlane, Edwin M.
Parkinson, Chris
van Heerden, Fanie R.
Crouch, Neil R.
Smith, Peter J.
Mancama, Dalu T.
Maharaj, Vinesh J.
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

OBJECTIVE: The roots of Anacyclus pyrethrum DC. (Compositae) are employed in Ayurvedic system of medicine as "Vajikaran Rasayana"--a category of drugs for vitality and virility. They are believed to have aphrodisiac action. The present investigation was undertaken to evaluate their effects on sexual behavior in male rats. METHODS: Thirty-two male Wistar rats were divided into control group, testosterone group, low-dose (50 mg/kg) petroleum ether extract (PEE) group and high-dose (100 mg/kg) PEE group.

Author(s): 
Sharma, Vikas
Thakur, Mayank
Chauhan, Nagendra S.
Dixit, Vinod Kumar
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called "Kayakalp", commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory property on skin diseases, the anti-cancer effect of C. anthelminticum seeds on skin cancer is less documented.

Author(s): 
Looi, Chung Yeng
Moharram, Bushra
Paydar, Mohammadjavad
Wong, Yi Li
Leong, Kok Hoong
Mohamad, Khalit
Arya, Aditya
Wong, Won Fen
Mustafa, Mohd Rais
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

OBJECTIVE: The roots of Anacyclus pyrethrum DC. (Compositae) are employed in Ayurvedic system of medicine as "Vajikaran Rasayana"--a category of drugs for vitality and virility. They are believed to have aphrodisiac action. The present investigation was undertaken to evaluate their effects on sexual behavior in male rats. METHODS: Thirty-two male Wistar rats were divided into control group, testosterone group, low-dose (50 mg/kg) petroleum ether extract (PEE) group and high-dose (100 mg/kg) PEE group.

Author(s): 
Sharma, Vikas
Thakur, Mayank
Chauhan, Nagendra S.
Dixit, Vinod Kumar
Publication Title: 
Pharmaceutical Biology

CONTEXT: Anacyclus pyrethrum DC (Compositae) roots, commonly known as Pellitory root and locally as akarkara, are widely recognized in the Indian traditional systems of medicine, Ayurveda, as a 'rasayana', i.e. a plant with immunomodulatory properties. OBJECTIVE: Evaluation of A. pyrethrum extract for its effect on normal and chemically suppressed immune systems in vivo. MATERIALS: Petroleum ether extract (PEE) of roots was tested at 50 and 100 mg/kg dose.

Author(s): 
Sharma, Vikas
Thakur, Mayank
Chauhan, Nagendra Singh
Dixit, Vinod Kumar
Publication Title: 
Phytotherapy research: PTR

Anacyclus pyrethrum (A. pyrethrum) has been used as Vajikaran Rasayana (aphrodisiac) in traditional Indian ayurvedic medicine to treat male sexual dysfunction, including infertility. Aphrodisiac activity may be due to an increase in the production or effect of androgens, so this study sought to evaluate the androgenic and spermatogenic potential of the alkylamide-rich ethanol solution extract. Male Wistar strain rats weighing between 150 and 180 g were completely randomized divided into five groups. The ethanol solution extract of A.

Author(s): 
Sharma, Vikas
Boonen, Jente
Spiegeleer, Bart De
Dixit, V. K.
Publication Title: 
Journal of Ethnopharmacology

ETHNOPHARMACOLOGICAL RELEVANCE: Seeds of Centratherum anthelminticum (Asteraceae) have been popularly used in Ayurvedic medicine to treat diabetes and skin disorders. Folk medicine from Rayalaseema (Andhra Pradesh, India) reported wide spread usage in diabetes. AIM OF THE STUDY: To investigate the hypoglycemic properties and mechanism of the methanolic fraction of C. anthelminticum seeds (CAMFs) on mouse β-TC6 pancreatic cell line and streptozotocin (STZ)-induced diabetic rat models. MATERIALS AND METHODS: We investigated the crude methanolic fraction of C.

Author(s): 
Arya, Aditya
Looi, Chung Yeng
Cheah, Shiau Chuen
Mustafa, Mohd Rais
Mohd, Mustafa Ali
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called "Kayakalp", commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory property on skin diseases, the anti-cancer effect of C. anthelminticum seeds on skin cancer is less documented.

Author(s): 
Looi, Chung Yeng
Moharram, Bushra
Paydar, Mohammadjavad
Wong, Yi Li
Leong, Kok Hoong
Mohamad, Khalit
Arya, Aditya
Wong, Won Fen
Mustafa, Mohd Rais
Publication Title: 
Pakistan journal of biological sciences: PJBS

Tridax procumbens L., Asteraceae, has been extensively used for various ailments in the Ayurvedic system of medicine. Previous studies have revealed remarkable phytoconstituents from Tridax procumbens L. with significant antioxidant activity. The aim of the present study is to measure the anti-DPPH activity of the purified isolated compounds from n butanol soluble part and ethyl acetate soluble part of successive methanolic extract of Tridax procumbens L.

Author(s): 
Saxena, Manjusha
Mir, Abrar Hussain
Sharma, Manik
Malla, Mohd Yousu
Qureshi, Sumeerah
Mir, Mohd Iqbal
Chaturvedi, Yogesh
Publication Title: 
American Journal of Physiology. Heart and Circulatory Physiology

Flavonoids within Scutellaria baicalensis may be potent antioxidants on the basis of our studies of S. baicalensis extract. To further this work, we studied the antioxidative effects of baicalein, a flavonoid component of S. baicalensis, in a chick cardiomyocyte model of reactive oxygen species (ROS) generation during hypoxia, simulated ischemia-reperfusion, or mitochondrial complex III inhibition with antimycin A. Oxidant stress was measured by oxidation of the intracellular probes 2',7'-dichlorofluorescin diacetate and dihydroethidium.

Author(s): 
Shao, Zuo-Hui
Vanden Hoek, Terry L.
Qin, Yimin
Becker, Lance B.
Schumacker, Paul T.
Li, Chang-Qing
Dey, Lucy
Barth, Eugene
Halpern, Howard
Rosen, Gerald M.
Yuan, Chun-Su

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