beta-Endorphin

Publication Title: 
Journal of Psychosomatic Research

A sound theoretical basis supported by scientifically measured physiological parameters is needed to gain medical support for animal-assisted therapy. Six neurochemicals associated with a decrease in blood pressure were measured in humans (n=18) and dogs (n=18) before and after positive interaction. Results (P<.05) indicated that in both species the neurochemicals involved with attention-seeking or attentionis egens behavior have increased. This information can be used as a rationale for animal-assisted therapy.

Author(s): 
Odendaal, J. S.
Publication Title: 
Physiology & Behavior

A series of experiments in male rabbits examined the influence of tonic immobility (animal hypnosis) on the opioid and pituitary-adrenal hormones. The aims of the experiments were to follow the temporal modifications in hormone parameters and to discriminate the effects of immobility from those of the manipulative procedure to induce the reaction. Results show that immobility elicits increases in plasma ACTH and beta-EP, but no modifications in pituitary beta-EP.

Author(s): 
Farabollini, F.
Facchinetti, F.
Lupo, C.
Carli, G.
Publication Title: 
Pain

Hypnosis and acupuncture can alleviate experimentally induced pain but the mechanism of analgesia remains unclear for both techniques. Experimental pain was induced by cold pressor test (CPT) in 8 male volunteers. Analgesic effect of hypnosis (HA) and acupuncture (AA) was assessed before and after double-blind administration of placebo or naloxone, in a prospective, cross-over study. We found that pain intensity was significantly lower with HA as compared with AA, both with naloxone (P less than 0.001) and placebo (P less than 0.001).

Author(s): 
Moret, V.
Forster, A.
Laverrière, M. C.
Lambert, H.
Gaillard, R. C.
Bourgeois, P.
Haynal, A.
Gemperle, M.
Buchser, E.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: Previously it was shown that a brief yoga-based lifestyle intervention was efficacious in reducing oxidative stress and risk of chronic diseases even in a short duration. The objective of this study was to assess the efficacy of this intervention in reducing stress and inflammation in patients with chronic inflammatory diseases. DESIGN: This study reports preliminary results from a nonrandomized prospective ongoing study with pre-post design.

Author(s): 
Yadav, Raj Kumar
Magan, Dipti
Mehta, Nalin
Sharma, Ratna
Mahapatra, Sushil Chandra
Publication Title: 
Pharmacology, Biochemistry, and Behavior

Maharishi-4 (M-4), an ayurvedic food supplement, was tested for anticarcinogenic and anticancer properties against 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in rats. The 6% M-4-supplemented diet protected DMBA-induced carcinogenesis by reducing both tumor incidence and multiplicity during initiation and promotion phases. The control animals who developed tumors when supplemented with M-4 diet for four weeks showed tumor regression in 60% of cases.

Author(s): 
Sharma, H. M.
Dwivedi, C.
Satter, B. C.
Gudehithlu, K. P.
Abou-Issa, H.
Malarkey, W.
Tejwani, G. A.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: Previously it was shown that a brief yoga-based lifestyle intervention was efficacious in reducing oxidative stress and risk of chronic diseases even in a short duration. The objective of this study was to assess the efficacy of this intervention in reducing stress and inflammation in patients with chronic inflammatory diseases. DESIGN: This study reports preliminary results from a nonrandomized prospective ongoing study with pre-post design.

Author(s): 
Yadav, Raj Kumar
Magan, Dipti
Mehta, Nalin
Sharma, Ratna
Mahapatra, Sushil Chandra
Publication Title: 
European Journal of Applied Physiology

Beta-endorphin (betaE) is an important reliever of pain. Various stressors and certain modalities of physiotherapy are potent inducers of the release of endogenous betaE to the blood stream. Most forms of exercise also increase blood betaE level, especially when exercise intensity involves reaching the anaerobic threshold and is associated with the elevation of serum lactate level. Age, gender, and mental activity during exercise also may influence betaE levels. Publications on the potential stimulating effect of manual therapy and massage on betaE release are controversial.

Author(s): 
Bender, Tamás
Nagy, György
Barna, István
Tefner, Ildikó
Kádas, Eva
Géher, Pál
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

The role of spinal manipulation in the relief of pain is becoming clearer and more demonstrable as time passes. One approach to this study is the effect of manipulation on the neurochemical mechanisms of antinociception. Chief among these is beta-endorphin, which has been found to produce a wide range of beneficial effects, especially analgesia. The intent of our study was to demonstrate the effect of spinal manipulation on plasma beta-endorphin levels. Three groups of male subjects were randomly created: the experimental, sham and control groups.

Author(s): 
Vernon, H. T.
Dhami, M. S.
Howley, T. P.
Annett, R.
Publication Title: 
Spine

This study examines the possibility of a humorally mediated analgesic response to spinal manipulative therapy by determination of plasma levels of beta-endorphin, adrenocorticotropic hormone (ACTH), and cortisol before and after intervention. Forty male subjects (20 symptomatic, 20 asymptomatic) were allocated into four equal groups. Two treatment groups were given spinal manipulative therapy, and two groups underwent a sham procedure.

Author(s): 
Christian, G. F.
Stanton, G. J.
Sissons, D.
How, H. Y.
Jamison, J.
Alder, B.
Fullerton, M.
Funder, J. W.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

The purpose of this study was to evaluate pain scores and plasma beta-endorphin levels following a single spinal adjustive manipulation in subjects with acute low back pain. Eighteen subjects were randomly assigned to either a control group, which received no treatment; a sham group, which received only light physical contact (touch); or an experimental group, which received an adjustive manipulation at a specific lumbar segment.

Author(s): 
Sanders, G. E.
Reinert, O.
Tepe, R.
Maloney, P.

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