Biocompatible Materials

Publication Title: 
Biomedical Materials (Bristol, England)

Adipose tissue engineering has recently gained significant attention from materials scientists as a result of the exponential growth of soft tissue filler procedures being performed within the clinic. While several injectable materials are currently being marketed for filling subcutaneous voids, they often face limited longevity due to rapid resorption. Their inability to encourage natural adipose formation or ingrowth necessitates repeated injections for a prolonged effect and thus classifies them as temporary fillers.

Author(s): 
Young, D. A.
Christman, K. L.
Publication Title: 
PloS One

Stem cells are increasingly the focus of translational research as well as having emerging roles in human cellular therapy. To support these uses there is a need for improved methods for in vivo cell localization and tracking. In this study, we examined the effects of cell labeling on the in vitro functionality of human adipose-derived mesenchymal stem cells. Our results provide a basis for future in vivo studies investigating implanted cell fate and longevity.

Author(s): 
Blaber, Sinead P.
Hill, Cameron J.
Webster, Rebecca A.
Say, Jana M.
Brown, Louise J.
Wang, Shih-Chang
Vesey, Graham
Herbert, Benjamin Ross
Publication Title: 
Journal of Biomedical Materials Research. Part A

The use of metal implants in dental and orthopedic surgery is continuously expanding and highly successful. While today longevity and load-bearing capacity of the implants fulfill the expectations of the patients, acceleration of osseointegration would be of particular benefit to shorten the period of convalescence. To further clarify the options to accelerate the kinetics of osseointegration, within this study, the osteogenic properties of structurally identical surfaces with different metal coatings were investigated.

Author(s): 
Hofstetter, Wilhelm
Sehr, Harald
de Wild, Michael
Portenier, Jeannette
Gobrecht, Jens
Hunziker, Ernst B.
Publication Title: 
The Journal of Surgical Research

BACKGROUND: Wound infection is a major problem in the medical community since many types of wounds are more prone to microbial contamination leading to infection. Triphala (a traditional ayurvedic herbal formulation) incorporated collagen sponge was investigated for its healing potential on infected dermal wound in albino rats. MATERIALS AND METHODS: Methanol extract of triphala was prepared and analyzed for the presence of catechin by high-pressure liquid chromatography analysis. Collagen sponge was prepared by incorporating triphala into collagen sponge.

Author(s): 
Kumar, Muthusamy Senthil
Kirubanandan, Shanmugam
Sripriya, Ramasamy
Sehgal, Praveen Kumar
Publication Title: 
Archives of Dermatology

BACKGROUND: Injection of calcium hydroxylapatite filler may result in nodule formation owing to superficial placement of the filler. Calcium hydroxylapatite nodules are difficult to reverse. Previously reported therapeutic options are limited and include intralesional triamcinolone, massage, needling, and excision, each with inconsistent results or potential for scarring. OBSERVATION: We have observed complete resolution of calcium hydroxylapatite nodules after a single treatment with fractional carbon dioxide laser.

Author(s): 
Reddy, Kavitha K.
Brauer, Jeremy A.
Anolik, Robert
Bernstein, Leonard
Brightman, Lori A.
Hale, Elizabeth
Karen, Julie
Weiss, Elliot
Geronemus, Roy G.
Publication Title: 
Revue De Stomatologie Et De Chirurgie Maxillo-Faciale

INTRODUCTION: Calvarial bone graft is widely used in cranio-maxillo-facial surgery. But the main sequel is an unsightly depression of the donor site. Reconstruction of the donor site using biomaterial could decrease this depression. The aim of this retrospective study was to evaluate the tolerance of biomaterials and the esthetic result of reconstruction. PATIENTS AND METHODS: During a 24-month period, 18 patients were reconstructed with Hydroset™ cement after calvarial bone harvesting. They were followed up for 24 months.

Author(s): 
Da Costa, G.
Goga, D.
Sury, F.
Laure, B.
Publication Title: 
Biological & Pharmaceutical Bulletin

Angiogenesis consists of the proliferation, migration, and differentiation of endothelial cells, and angiogenic factors and matrix protein interactions modulate this process. The aim of this study was to determine the angiogenic properties of Uncaria rhynchophylla. Uncaria rhynchophylla significantly enhanced human umbilical vein endothelial cells (HUVECs) proliferation in a dose-dependent manner.

Author(s): 
Choi, Do-Young
Huh, Jeong-Eun
Lee, Jae-Dong
Cho, Eun-Mi
Baek, Yong-Hyeon
Yang, Ha-Ru
Cho, Yoon-Je
Kim, Kang-Il
Kim, Deog-Yoon
Park, Dong-Suk
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