Bioengineering

Publication Title: 
Rejuvenation Research

According to the Homeric Hymn to Aphrodite, when Eos asked Zeus for Tithonus to be granted immortality, she forgot to ask for eternal youth. Applied Healthspan Engineering (AHE) seeks to address this problem. All organisms have a minimal level of functional reserve required to sustain life that eventually declines to a point incompatible with survival at death. AHE seeks to maintain or restore optimal functional reserve of critical tissues and organs. Tissue reserve correlates with well being.

Author(s): 
Larrick, James W.
Mendelsohn, Andrew
Publication Title: 
Journal of Cancer Education: The Official Journal of the American Association for Cancer Education

Many students in bioengineering and medical physics doctoral programs plan careers in translational research. However, while such students generally have strong quantitative abilities, they often lack experience with the culture, communication norms, and practice of bedside medicine. This may limit students' ability to function as members of multidisciplinary translational research teams.

Author(s): 
Woods, Kendra V.
Peek, Kathryn E.
Richards-Kortum, Rebecca
Publication Title: 
Journal of Agricultural and Food Chemistry

Consumption of tomato products has been associated with decreased risks of chronic diseases such as cardiovascular disease and cancer, and therefore the biological functions of tomato carotenoids such as lycopene, phytoene, and phytofluene are being investigated. To study the absorption, distribution, metabolism, and excretion of these carotenoids, a bioengineered Escherichia coli model was evaluated for laboratory-scale production of stable isotope-labeled carotenoids.

Author(s): 
Lu, Chi-Hua
Choi, Jin-Ho
Engelmann Moran, Nancy
Jin, Yong-Su
Erdman, John W.
Publication Title: 
Annual Review of Chemical and Biomolecular Engineering

A major objective of synthetic biology is to make the process of designing genetically encoded biological systems more systematic, predictable, robust, scalable, and efficient. Examples of genetic systems in the field vary widely in terms of operating hosts, compositional approaches, and network complexity, ranging from simple genetic switches to search-and-destroy systems.

Author(s): 
Wang, Yen-Hsiang
Wei, Kathy Y.
Smolke, Christina D.
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