Biometry

Publication Title: 
Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopädie: Organ/Official Journal Deutsche Gesellschaft Für Kieferorthopädie

In this review article we examine the question as to which parameters of facial attraction are amenable to measurement and which tools are available to perform these measurements. The evaluation of facial images, artistic standards, cephalometry, and anthropometry are discussed. Furthermore, we consider how the attractiveness of a face is influenced by symmetry, averageness and distinguishing features such as dental esthetics or gender specific characteristics. There is a shared concept of what constitutes an "ideal" face.

Author(s): 
Hönn, Mirjam
Göz, Gernot
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVE: To compute quantitative estimates of the tridosha--the qualitative characterization that constitutes the core of diagnosis and treatment in Ayurveda--to provide a basis for biostatistical analysis of this ancient Indian science, which is a promising field of alternative medicine. SUBJECTS: The data sources were 280 persons from among the residents and visitors/training students at the Brahmvarchas Research Centre and Shantikuj, Hardwar, India.

Author(s): 
Joshi, Rajani R.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVE: To compute quantitative estimates of the tridosha--the qualitative characterization that constitutes the core of diagnosis and treatment in Ayurveda--to provide a basis for biostatistical analysis of this ancient Indian science, which is a promising field of alternative medicine. SUBJECTS: The data sources were 280 persons from among the residents and visitors/training students at the Brahmvarchas Research Centre and Shantikuj, Hardwar, India.

Author(s): 
Joshi, Rajani R.
Publication Title: 
Biometrics

In this article we study a joint model for longitudinal measurements and competing risks survival data. Our joint model provides a flexible approach to handle possible nonignorable missing data in the longitudinal measurements due to dropout. It is also an extension of previous joint models with a single failure type, offering a possible way to model informatively censored events as a competing risk.

Author(s): 
Elashoff, Robert M.
Li, Gang
Li, Ning
Publication Title: 
Biometrical Journal. Biometrische Zeitschrift

Existing methods for joint modeling of longitudinal measurements and survival data can be highly influenced by outliers in the longitudinal outcome. We propose a joint model for analysis of longitudinal measurements and competing risks failure time data which is robust in the presence of outlying longitudinal observations during follow-up. Our model consists of a linear mixed effects sub-model for the longitudinal outcome and a proportional cause-specific hazards frailty sub-model for the competing risks data, linked together by latent random effects.

Author(s): 
Li, Ning
Elashoff, Robert M.
Li, Gang
Publication Title: 
Biometrical Journal. Biometrische Zeitschrift

We explore a Bayesian approach to selection of variables that represent fixed and random effects in modeling of longitudinal binary outcomes with missing data caused by dropouts. We show via analytic results for a simple example that nonignorable missing data lead to biased parameter estimates. This bias results in selection of wrong effects asymptotically, which we can confirm via simulations for more complex settings.

Author(s): 
Li, Ning
Daniels, Michael J.
Li, Gang
Elashoff, Robert M.
Publication Title: 
Vaccine

Negative studies of vaccine adverse events occur with some frequency in the published literature. They serve important roles in fending off claims posed by the anti-vaccine movement and in reinforcing public health efforts to prevent diseases. Still, negative studies frequently suffer from concerns of adequate sample size. The double-significance Neyman-Pearson formula for sample size calculation that is now in vogue results in immense sample sizes that can lead to illogical interpretations. The late Professor Alvan R.

Author(s): 
Jacobson, Robert M.
Poland, Gregory A.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

A discussion is presented of the four-quadrant weight scale; a postural analysis unit developed by the chiropractic profession to evaluate weight-bearing in the sagittal and frontal body planes. This report summarizes the technical description of the apparatus and attempts to establish a standardized procedural protocol. The normal and several aberrant weight-bearing patterns, and their clinical implications are discussed. Possible research applications for the future are suggested.

Author(s): 
Vernon, H.
Grice, A.
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

OBJECTIVE: To investigate the scientificity of patient-reported outcome (PRO) scale for myasthenia gravis (MG), which was used to evaluate the clinical effects of traditional Chinese and Western medicine treatment on MG patients. Psychometric performance of the MG-PRO scale was also expected to be evaluated in this study. METHODS: A total of 100 MG patients and 100 healthy people were face-to-face interviewed by well-trained investigators, and the data of MG-PRO scale were collected.

Author(s): 
Chen, Xin-lin
Liu, Feng-bin
Guo, Li
Liu, Xiao-bin
Publication Title: 
Statistics in Medicine

Childhood acute lymphoblastic leukaemia is treated with long-term intensive chemotherapy. During the latter part of the treatment, the maintenance therapy, the patients receive oral doses of two cytostatics. The doses are tailored to blood counts measured on a weekly basis, and the treatment is therefore highly dynamic. In 1992-1996, the Nordic Society of Paediatric Haematology and Oncology (NOPHO) conducted a randomised study (NOPHO-ALL-92) to investigate the effect of a new and more sophisticated dynamic treatment strategy.

Author(s): 
Rosthøj, S.
Keiding, N.
Schmiegelow, K.

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