Blinding

Publication Title: 
World Journal of Methodology

The increasing number and sophistication of available psychotherapies suggests that a critical appraisal of the methodological issues of psychotherapy studies is highly needed.

Author(s): 
Chiesa, Alberto
Publication Title: 
International Journal of Epidemiology

BACKGROUND: Blinding patients in clinical trials is a key methodological procedure, but the expected degree of bias due to nonblinded patients on estimated treatment effects is unknown. METHODS: Systematic review of randomized clinical trials with one sub-study (i.e. experimental vs control) involving blinded patients and another, otherwise identical, sub-study involving nonblinded patients. Within each trial, we compared the difference in effect sizes (i.e. standardized mean differences) between the sub-studies.

Author(s): 
Hróbjartsson, Asbjørn
Emanuelsson, Frida
Skou Thomsen, Ann Sofia
Hilden, Jørgen
Brorson, Stig
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