Blood Cell Count

Publication Title: 
Psychophysiology

We aimed to unravel the clinical benefits and the plausible underlying psychophysiological mechanism based on available randomized controlled trials (RCTs).

Author(s): 
Ng, Bobby H. P.
Tsang, Hector W. H.
Publication Title: 
Journal of Clinical Pathology
Author(s): 
Ghosh, M. L.
Hudson, G.
Blackburn, E. K.
Publication Title: 
Thrombosis Et Diathesis Haemorrhagica

Various parameters of the coagulation system have been monitored in patients with Christmas disease following the infusion of clotting factor concentrates. Significant reduction of clotting factor VIII and serum antithrombin III were observed in each of the five studies, whilst the plasma fibrinogen level fell in four subjects. The induced abnormalities were shortlived and there were no clinical sequelae. Further studies are required to assess the effects of similar concentrates in patients with liver disease.

Author(s): 
Preston, F. E.
Winfield, D. A.
Malia, R. G.
Blackburn, E. K.
Publication Title: 
Journal of Neurology, Neurosurgery, and Psychiatry

Three cases with intracranial lesions developed evidence of disseminated intravascular coagulation which was confirmed at necropsy. The factors engendering this state, including release of potent thromboplastin from neural tissue are discussed and the danger of this intermediary mechanism of disease increasing the mortality of intracranial disease is demonstrated. Careful haematological investigation of all patients with intracranial disease is therefore advised, especially if they manifest evidence of a bleeding tendency.

Author(s): 
Preston, F. E.
Malia, R. G.
Sworn, M. J.
Timperley, W. R.
Blackburn, E. K.
Publication Title: 
Thrombosis and Haemostasis

Evidence has been sought of activation of the coagulation system in two groups of patients following the infusion of two heparinised clotting factor concentrates. No changes were detected in 13 patients with mild hepatic dysfunction. In six studies on patients with Christmas disease induced abnormalities occurred in only one. Activation of the coagulation mechanism did not occur in another individual who had received the same batch of material.

Author(s): 
Preston, F. E.
Malia, R. G.
Lilleyman, J. S.
Blackburn, E. K.
Publication Title: 
Revue Française D'odonto-Stomatologie
Author(s): 
Dufour, J.
D'Auteuil, P.
Dionne, P.
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

Artemether, an efficacious antimalarial drug, effectively prevents patent schistosome infections and morbidity, as established in laboratory models and in clinical trials. In view of concern about the potential long-term toxicity, rats were treated orally with 80 mg/kg artemether once every 2 weeks for 5 months. After the final treatment, routine blood test results were normal except for reversible reductions of reticulocyte counts and reversible increases in hemoglobin levels.

Author(s): 
Xiao, Shuhua
Yang, Yuanqing
You, Qiqing
Utzinger, Jürg
Guo, Huifang
Peiying, Jiao
Mei, Jinying
Guo, Jian
Bergquist, Robert
Tanner, Marcel
Publication Title: 
Malaria Journal

BACKGROUND: Sickle cell disease (SCD) is a genetic disorder common in malaria endemic areas. In endemic areas, malaria is a major cause of morbidity and mortality among SCD patients. This suggests the need for prompt initiation of efficacious anti-malarial therapy in SCD patients with acute malaria. However, there is no information to date, on the efficacy or safety of artemisinin combination therapy when used for malaria treatment in SCD patients.

Author(s): 
Adjei, George O.
Goka, Bamenla Q.
Enweronu-Laryea, Christabel C.
Rodrigues, Onike P.
Renner, Lorna
Sulley, Abdul M.
Alifrangis, Michael
Khalil, Insaf
Kurtzhals, Jorgen A.
Publication Title: 
The Journal of Toxicological Sciences

The aim of the present investigation deals with the hematology and hepatorenal function of Caesalpinia bonducella Flem. and Bauhinia racemosa Lam. belonging to the Family: Caesalpiniaceae, and used in the traditional system of medicine. The tribal people of Kolli Hills, Tamil Nadu, India, use the leaves of Caesalpinia bonducella and the stem bark of Bauhinia racemosa in combination with some other herbs for the treatment of various tumors, liver disorders, inflammation and some other diseases. In ancient Ayurveda medicine these plants were mentioned to possess antitumor agents.

Author(s): 
Kumar, Ramanathan Sambath
Gupta, Malaya
Mazumdar, Upal Kanti
Rajeshwar, Yerra
Kumar, Thangavel Siva
Gomathi, Periaswamy
Roy, Rathnamala
Publication Title: 
The Journal of Toxicological Sciences

The aim of the present investigation deals with the hematology and hepatorenal function of Caesalpinia bonducella Flem. and Bauhinia racemosa Lam. belonging to the Family: Caesalpiniaceae, and used in the traditional system of medicine. The tribal people of Kolli Hills, Tamil Nadu, India, use the leaves of Caesalpinia bonducella and the stem bark of Bauhinia racemosa in combination with some other herbs for the treatment of various tumors, liver disorders, inflammation and some other diseases. In ancient Ayurveda medicine these plants were mentioned to possess antitumor agents.

Author(s): 
Kumar, Ramanathan Sambath
Gupta, Malaya
Mazumdar, Upal Kanti
Rajeshwar, Yerra
Kumar, Thangavel Siva
Gomathi, Periaswamy
Roy, Rathnamala

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